Your browser doesn't support javascript.
loading
Proprotein convertase PCSK9 affects expression of key surface proteins in human pancreatic beta cells via intracellular and extracellular regulatory circuits.
Saitoski, Kevin; Ryaboshapkina, Maria; Hamza, Ghaith M; Jarnuczak, Andrew F; Berthault, Claire; Carlotti, Françoise; Armanet, Mathieu; Sengupta, Kaushik; Underwood, Christina Rye; Andersson, Shalini; Guillas, Isabelle; Le Goff, Wilfried; Scharfmann, Raphael.
Affiliation
  • Saitoski K; Université de Paris, Institut Cochin, INSERM U1016, CNRS UMR 8104, Paris, France.
  • Ryaboshapkina M; Translational Science and Experimental Medicine, Research and Early Development, Cardiovascular, Renal and Metabolism (CVRM), BioPharmaceuticals R&D, AstraZeneca, Gothenburg, Sweden.
  • Hamza GM; Discovery Sciences, AstraZeneca, Boston, Massachusetts, USA; Molecular, Cellular and Biomedical Sciences, University of New Hampshire, Durham, New Hampshire, USA.
  • Jarnuczak AF; Quantitative Biology, Discovery Sciences, BioPharmaceuticals R&D, AstraZeneca, Cambridge, United Kingdom.
  • Berthault C; Université de Paris, Institut Cochin, INSERM U1016, CNRS UMR 8104, Paris, France.
  • Carlotti F; Division of Nephrology, Department of Internal Medicine, Leiden University Medical Center, Leiden, The Netherlands.
  • Armanet M; Cell Therapy Unit, Hôpital Saint Louis, AP-HP, Université de Paris, Paris, France.
  • Sengupta K; Alliance Management, Business Development and Licensing, Biopharmaceuticals R&D, Astra Zeneca, Gothenburg, Sweden.
  • Underwood CR; Bioscience Metabolism, Research and Early Development, Cardiovascular, Renal and Metabolism (CVRM), BioPharmaceuticals R&D, AstraZeneca, Cambridge, United Kingdom.
  • Andersson S; Oligonucleotide Discovery, Discovery Sciences, BioPharmaceuticals R&D, AstraZeneca, Gothenburg, Sweden.
  • Guillas I; Sorbonne Université, Inserm, Institute of Cardiometabolism and Nutrition (ICAN), UMR_S1166, Paris, France.
  • Le Goff W; Sorbonne Université, Inserm, Institute of Cardiometabolism and Nutrition (ICAN), UMR_S1166, Paris, France.
  • Scharfmann R; Université de Paris, Institut Cochin, INSERM U1016, CNRS UMR 8104, Paris, France. Electronic address: raphael.scharfmann@inserm.fr.
J Biol Chem ; 298(7): 102096, 2022 07.
Article in En | MEDLINE | ID: mdl-35660019
Subject(s)
Key words
Fulltext
Add to My VHL
Print
XML
PubMed Links
Search on Google

Full text: 1 Collection: 01-internacional Database: MEDLINE Main subject: Insulin-Secreting Cells / Proprotein Convertase 9 / Membrane Proteins Limits: Humans Language: En Journal: J Biol Chem Year: 2022 Document type: Article Affiliation country: France Country of publication: United States
Fulltext
Add to My VHL
Print
XML
PubMed Links
Search on Google

Full text: 1 Collection: 01-internacional Database: MEDLINE Main subject: Insulin-Secreting Cells / Proprotein Convertase 9 / Membrane Proteins Limits: Humans Language: En Journal: J Biol Chem Year: 2022 Document type: Article Affiliation country: France Country of publication: United States