Exercise, inflammation and acute cardiovascular events.
Exerc Immunol Rev
; 28: 93-103, 2022.
Article
in En
| MEDLINE
| ID: mdl-35671219
Individuals who participate in regular exercise over time have a markedly reduced risk of cardiovascular disease. Paradoxically, in susceptible individuals with underlying, often undiagnosed, disease states, exercise may acutely increase an individual's risk of cardiovascular events during and immediately following physical exertion. Exercise is thought to evoke conditions that trigger atheromatous plaque rupture or trigger life threatening arrhythmias in individuals with pre-existing, vulnerable coronary artery and inherited cardiovascular disease respectively. This transient increased risk may be driven by the inflammatory trigger provided by physical exertion where exercise is associated with an upregulation of inflammatory mediators in the acute phase. Conversely, habitual exercise can lead to a modulation of the inflammatory response over time. This review explores: exercise related inflammation; acute cardiovascular events related to exercise and strategies to mitigate these risks.
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Collection:
01-internacional
Database:
MEDLINE
Main subject:
Cardiovascular Diseases
Type of study:
Etiology_studies
Limits:
Humans
Language:
En
Journal:
Exerc Immunol Rev
Journal subject:
ALERGIA E IMUNOLOGIA
Year:
2022
Document type:
Article
Country of publication:
Germany