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Generating Complete Genome Assemblies of Candida auris.
Shea, Terrance P; Cuomo, Christina A.
Affiliation
  • Shea TP; Infectious Disease and Microbiome Program, Broad Institute of MIT and Harvard, Cambridge, MA, USA.
  • Cuomo CA; Infectious Disease and Microbiome Program, Broad Institute of MIT and Harvard, Cambridge, MA, USA. cuomo@broadinstitute.org.
Methods Mol Biol ; 2517: 205-214, 2022.
Article in En | MEDLINE | ID: mdl-35674956
ABSTRACT
Genomic studies of Candida auris are underpinned by the generation of high-quality genome assemblies. These reference genomes have been essential for investigations of the evolution and epidemiology of this emerging fungal pathogen. In addition to genomic epidemiology studies of local outbreaks and analysis of the global emergence of this species, comparisons of genomes of isolates from the five major clades have revealed differences in gene content and genomic structure. Here, we provide a detailed protocol for generating complete genome assemblies for C. auris.
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Full text: 1 Collection: 01-internacional Database: MEDLINE Main subject: Candida / Candidiasis Language: En Journal: Methods Mol Biol Journal subject: BIOLOGIA MOLECULAR Year: 2022 Document type: Article Affiliation country: United States

Full text: 1 Collection: 01-internacional Database: MEDLINE Main subject: Candida / Candidiasis Language: En Journal: Methods Mol Biol Journal subject: BIOLOGIA MOLECULAR Year: 2022 Document type: Article Affiliation country: United States