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An interdisciplinary consensus on the management of brain metastases in patients with renal cell carcinoma.
Hasanov, Elshad; Yeboa, Debra Nana; Tucker, Mathew D; Swanson, Todd A; Beckham, Thomas Hendrix; Rini, Brian; Ene, Chibawanye I; Hasanov, Merve; Derks, Sophie; Smits, Marion; Dudani, Shaan; Heng, Daniel Y C; Brastianos, Priscilla K; Bex, Axel; Hanalioglu, Sahin; Weinberg, Jeffrey S; Hirsch, Laure; Carlo, Maria I; Aizer, Ayal; Brown, Paul David; Bilen, Mehmet Asim; Chang, Eric Lin; Jaboin, Jerry; Brugarolas, James; Choueiri, Toni K; Atkins, Michael B; McGregor, Bradley A; Halasz, Lia M; Patel, Toral R; Soltys, Scott G; McDermott, David F; Elder, James Bradley; Baskaya, Mustafa K; Yu, James B; Timmerman, Robert; Kim, Michelle Miran; Mut, Melike; Markert, James; Beal, Kathryn; Tannir, Nizar M; Samandouras, George; Lang, Frederick F; Giles, Rachel; Jonasch, Eric.
Affiliation
  • Hasanov E; Division of Cancer Medicine, The University of Texas MD Anderson Cancer Center, Houston, Texas.
  • Yeboa DN; Department of Radiation Oncology, Division of Radiation Oncology, The University of Texas MD Anderson Cancer Center, Houston, Texas.
  • Tucker MD; Department of Medicine, Division of Hematology and Oncology, Vanderbilt University Medical Center, Nashville, Tennessee.
  • Swanson TA; Department of Radiation Oncology, Division of Radiation Oncology, The University of Texas MD Anderson Cancer Center, Houston, Texas.
  • Beckham TH; Department of Radiation Oncology, Division of Radiation Oncology, The University of Texas MD Anderson Cancer Center, Houston, Texas.
  • Rini B; Department of Medicine, Division of Hematology and Oncology, Vanderbilt University Medical Center, Nashville, Tennessee.
  • Ene CI; Department of Neurosurgery, Division of Surgery, The University of Texas MD Anderson Cancer Center, Houston, Texas.
  • Hasanov M; Division of Cancer Medicine, The University of Texas MD Anderson Cancer Center, Houston, Texas.
  • Derks S; Department of Radiology and Nuclear Medicine, Erasmus Medical Center, University Medical Center Rotterdam, Rotterdam, the Netherlands.
  • Smits M; Department of Radiology and Nuclear Medicine, Erasmus Medical Center, University Medical Center Rotterdam, Rotterdam, the Netherlands.
  • Dudani S; Division of Oncology/Hematology, William Osler Health System, Brampton, Ontario, Canada.
  • Heng DYC; Tom Baker Cancer Center, University of Calgary, Calgary, Alberta, Canada.
  • Brastianos PK; Division of Neuro-Oncology, Massachusetts General Hospital, Harvard Medical School, Boston, Massachusetts.
  • Bex A; The Royal Free London National Health Service Foundation Trust, London, United Kingdom.
  • Hanalioglu S; University College London Division of Surgery and Interventional Science, London, United Kingdom.
  • Weinberg JS; Department of Urology, The Netherlands Cancer Institute, Antoni van Leeuwenhoek Hospital, Amsterdam, the Netherlands.
  • Hirsch L; Department of Neurosurgery, Hacettepe University Faculty of Medicine, Ankara, Turkey.
  • Carlo MI; Department of Neurosurgery, Division of Surgery, The University of Texas MD Anderson Cancer Center, Houston, Texas.
  • Aizer A; Department of Medical Oncology, Cochin University Hospital, Public Assistance Hospital of Paris, Paris, France.
  • Brown PD; Lank Center for Genitourinary Oncology, Dana-Farber Cancer Institute, Boston, Massachusetts.
  • Bilen MA; Genitourinary Oncology Service, Department of Medicine, Memorial Sloan Kettering Cancer Center, New York, New York.
  • Chang EL; Department of Radiation Oncology, Brigham and Women's Hospital, Dana-Farber Cancer Institute, Harvard Medical School, Boston, Massachusetts.
  • Jaboin J; Department of Radiation Oncology, Mayo Clinic, Rochester, Minnesota.
  • Brugarolas J; Department of Hematology and Medical Oncology, Emory University School of Medicine, Atlanta, Georgia.
  • Choueiri TK; Winship Cancer Institute of Emory University, Atlanta, Georgia.
  • Atkins MB; Department of Radiation Oncology, University of Southern California, Keck School of Medicine, California, Los Angeles.
  • McGregor BA; Department of Radiation Medicine, Oregon Health & Science University, Portland, Oregon.
  • Halasz LM; Kidney Cancer Program, Simmons Comprehensive Cancer Center, The University of Texas Southwestern Medical Center, Dallas, Texas.
  • Patel TR; Division of Hematology/Oncology, Department of Internal Medicine, The University of Texas Southwestern Medical Center, Dallas, Texas.
  • Soltys SG; Lank Center for Genitourinary Oncology, Dana-Farber Cancer Institute, Boston, Massachusetts.
  • McDermott DF; Lombardi Comprehensive Cancer Center, MedStar Georgetown University Hospital, Washington, DC.
  • Elder JB; Lank Center for Genitourinary Oncology, Dana-Farber Cancer Institute, Boston, Massachusetts.
  • Baskaya MK; Department of Radiation Oncology, University of Washington, Seattle, Washington.
  • Yu JB; Kidney Cancer Program, Simmons Comprehensive Cancer Center, The University of Texas Southwestern Medical Center, Dallas, Texas.
  • Timmerman R; Department of Neurosurgery, The University of Texas Southwestern Medical Center, Dallas, Texas.
  • Kim MM; Department of Radiation Oncology, Stanford Cancer Institute, Stanford, California.
  • Mut M; Division of Medical Oncology, Beth Israel Deaconess Medical Center, Boston, Massachusetts.
  • Markert J; Department of Neurological Surgery, Ohio State University Wexner Medical Center, Columbus, Ohio.
  • Beal K; Department of Neurological Surgery, University of Wisconsin-Madison, School of Medicine and Public Health, Madison, Wisconsin.
  • Tannir NM; Department of Therapeutic Radiology, Yale University School of Medicine, New Haven, Connecticut.
  • Samandouras G; Kidney Cancer Program, Simmons Comprehensive Cancer Center, The University of Texas Southwestern Medical Center, Dallas, Texas.
  • Lang FF; Department of Radiation Oncology, The University of Texas Southwestern Medical Center, Dallas, Texas.
  • Giles R; Department of Radiation Oncology, University of Michigan, Ann Arbor, Michigan.
  • Jonasch E; Department of Neurosurgery, Hacettepe University Faculty of Medicine, Ankara, Turkey.
CA Cancer J Clin ; 72(5): 454-489, 2022 09.
Article in En | MEDLINE | ID: mdl-35708940
ABSTRACT
Brain metastases are a challenging manifestation of renal cell carcinoma. We have a limited understanding of brain metastasis tumor and immune biology, drivers of resistance to systemic treatment, and their overall poor prognosis. Current data support a multimodal treatment strategy with radiation treatment and/or surgery. Nonetheless, the optimal approach for the management of brain metastases from renal cell carcinoma remains unclear. To improve patient care, the authors sought to standardize practical management strategies. They performed an unstructured literature review and elaborated on the current management strategies through an international group of experts from different disciplines assembled via the network of the International Kidney Cancer Coalition. Experts from different disciplines were administered a survey to answer questions related to current challenges and unmet patient needs. On the basis of the integrated approach of literature review and survey study results, the authors built algorithms for the management of single and multiple brain metastases in patients with renal cell carcinoma. The literature review, consensus statements, and algorithms presented in this report can serve as a framework guiding treatment decisions for patients. CA Cancer J Clin. 2022;72454-489.
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Full text: 1 Collection: 01-internacional Database: MEDLINE Main subject: Brain Neoplasms / Carcinoma, Renal Cell / Kidney Neoplasms Type of study: Qualitative_research Limits: Humans Language: En Journal: CA Cancer J Clin Year: 2022 Document type: Article
Fulltext
Add to My VHL
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Full text: 1 Collection: 01-internacional Database: MEDLINE Main subject: Brain Neoplasms / Carcinoma, Renal Cell / Kidney Neoplasms Type of study: Qualitative_research Limits: Humans Language: En Journal: CA Cancer J Clin Year: 2022 Document type: Article