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Cobimetinib in Pediatric and Young Adult Patients with Relapsed or Refractory Solid Tumors (iMATRIX-cobi): A Multicenter, Phase I/II Study.
Trippett, Tanya; Toledano, Helen; Campbell Hewson, Quentin; Verschuur, Arnauld; Langevin, Anne-Marie; Aerts, Isabelle; Howell, Lisa; Gallego, Soledad; Rossig, Claudia; Smith, Amy; Patel, Darshak; Pereira, Leonardo R; Cheeti, Sravanthi; Musib, Luna; Hutchinson, Katherine E; Devlin, Clare; Bernardi, Ronald; Geoerger, Birgit.
Affiliation
  • Trippett T; Department of Pediatrics, Memorial Sloan Kettering Cancer Center, 1275 York Avenue, New York, NY, 10065, USA. trippet1@MSKCC.ORG.
  • Toledano H; Department of Pediatric Hematology-Oncology, Schneider Children's Medical Center, Sackler School of Medicine, Tel Aviv University, Tel Aviv, Israel.
  • Campbell Hewson Q; Department of Paediatric and Adolescent Oncology, The Great North Children's Hospital, Newcastle Upon Tyne, UK.
  • Verschuur A; Assistance Publique-Hopitaux de Marseille, Pediatric Oncology, Timone Children's Hospital, Marseille, France.
  • Langevin AM; Department of Pediatrics, UT Health San Antonio, San Antonio, TX, USA.
  • Aerts I; Oncology Center SIREDO, Institut Curie, PSL Research University, Paris, France.
  • Howell L; Paediatric Oncology, Alder Hey Children's NHS Foundation Trust, Liverpool, UK.
  • Gallego S; Paediatric Oncology, Hospital Universitari Vall d'Hebron, Barcelona, Spain.
  • Rossig C; Pediatric Hematology and Oncology, University Children's Hospital Muenster, Muenster, Germany.
  • Smith A; Haley Center for Children's Cancer and Blood Disorders, Orlando-Health Arnold Palmer Hospital for Children, Orlando, FL, USA.
  • Patel D; Product Development, Biometrics, Biostatistics, F. Hoffmann-La Roche Ltd, Mississauga, ON, Canada.
  • Pereira LR; Parexel International Ltd, Ottawa, ON, Canada.
  • Cheeti S; Product Development Safety, Roche Products Ltd, Welwyn, UK.
  • Musib L; Clinical Pharmacology, Genentech, Inc., South San Francisco, CA, USA.
  • Hutchinson KE; Clinical Pharmacology, Genentech, Inc., South San Francisco, CA, USA.
  • Devlin C; Arrivent Biopharma, Newtown Square, PA, USA.
  • Bernardi R; Oncology Biomarker Development, Genentech, Inc., South San Francisco, CA, USA.
  • Geoerger B; Product Development Oncology, Roche Products Ltd, Welwyn, UK.
Target Oncol ; 17(3): 283-293, 2022 05.
Article in En | MEDLINE | ID: mdl-35715627

Full text: 1 Collection: 01-internacional Database: MEDLINE Main subject: Piperidines / Azetidines / Neoplasms Type of study: Clinical_trials Limits: Adolescent / Adult / Child / Child, preschool / Humans Language: En Journal: Target Oncol Journal subject: NEOPLASIAS Year: 2022 Document type: Article Affiliation country: United States Country of publication: France

Full text: 1 Collection: 01-internacional Database: MEDLINE Main subject: Piperidines / Azetidines / Neoplasms Type of study: Clinical_trials Limits: Adolescent / Adult / Child / Child, preschool / Humans Language: En Journal: Target Oncol Journal subject: NEOPLASIAS Year: 2022 Document type: Article Affiliation country: United States Country of publication: France