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Metabolomic Evaluation of N-Acetyl-p-Benzoquinone Imine Protein Adduct Formation with Therapeutic Acetaminophen Administration: Sex-based Physiologic Differences.
Arnold, Cosby G; Dylla, Layne; Monte, Andrew A; Heard, Kennon; Heard, Susan; D'Alessandro, Angelo; Reynolds, Kate; Dart, Richard; Rumack, Barry; Sonn, Brandon.
Affiliation
  • Arnold CG; Department of Emergency Medicine, University of Colorado School of Medicine, University of Colorado Denver-Anschutz Medical Center, Mail Stop B-215, 12401 East 17thAvenue, Aurora, CO, 80045, USA. cosby.arnold@cuanschutz.edu.
  • Dylla L; Department of Emergency Medicine, University of Colorado School of Medicine, University of Colorado Denver-Anschutz Medical Center, Mail Stop B-215, 12401 East 17thAvenue, Aurora, CO, 80045, USA.
  • Monte AA; Department of Emergency Medicine, University of Colorado School of Medicine, University of Colorado Denver-Anschutz Medical Center, Mail Stop B-215, 12401 East 17thAvenue, Aurora, CO, 80045, USA.
  • Heard K; Rocky Mountain Poison & Drug Center, Denver Health and Hospital Authority, 1391 Speer Blvd Unit 600, Denver, CO, 80204, USA.
  • Heard S; Department of Emergency Medicine, University of Colorado School of Medicine, University of Colorado Denver-Anschutz Medical Center, Mail Stop B-215, 12401 East 17thAvenue, Aurora, CO, 80045, USA.
  • D'Alessandro A; Rocky Mountain Poison & Drug Center, Denver Health and Hospital Authority, 1391 Speer Blvd Unit 600, Denver, CO, 80204, USA.
  • Reynolds K; Rocky Mountain Poison & Drug Center, Denver Health and Hospital Authority, 1391 Speer Blvd Unit 600, Denver, CO, 80204, USA.
  • Dart R; Division of Bioinformatics & Personalized Medicine, University of Colorado School of Medicine, 13001 E 17th Place, Fitzimons Building, 5th floor, #563, Aurora, CO, 80045, USA.
  • Rumack B; Rocky Mountain Poison & Drug Center, Denver Health and Hospital Authority, 1391 Speer Blvd Unit 600, Denver, CO, 80204, USA.
  • Sonn B; Rocky Mountain Poison & Drug Center, Denver Health and Hospital Authority, 1391 Speer Blvd Unit 600, Denver, CO, 80204, USA.
J Med Toxicol ; 18(4): 297-310, 2022 10.
Article in En | MEDLINE | ID: mdl-35751009
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Full text: 1 Collection: 01-internacional Database: MEDLINE Main subject: Benzoquinones / Analgesics, Non-Narcotic / Alanine Transaminase / Metabolome / Imines / Acetaminophen Type of study: Observational_studies / Prognostic_studies / Risk_factors_studies Limits: Adult / Female / Humans / Male Language: En Journal: J Med Toxicol Journal subject: TOXICOLOGIA Year: 2022 Document type: Article Affiliation country: United States Country of publication: United States
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Full text: 1 Collection: 01-internacional Database: MEDLINE Main subject: Benzoquinones / Analgesics, Non-Narcotic / Alanine Transaminase / Metabolome / Imines / Acetaminophen Type of study: Observational_studies / Prognostic_studies / Risk_factors_studies Limits: Adult / Female / Humans / Male Language: En Journal: J Med Toxicol Journal subject: TOXICOLOGIA Year: 2022 Document type: Article Affiliation country: United States Country of publication: United States