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Identification of 2-(4-N,N-Dimethylaminophenyl)-5-methyl-1-phenethyl-1H-benzimidazole targeting HIV-1 CA capsid protein and inhibiting HIV-1 replication in cellulo.
Alvarez, Guzmán; van Pul, Lisa; Robert, Xavier; Artía, Zoraima; van Nuenen, Ad C; Long, Mathieu; Sierra, Natalia; Porcal, Williams; Kootstra, Neeltje A; Guillon, Christophe.
Affiliation
  • Alvarez G; Laboratorio de Moléculas Bioactivas, Departamento de Ciencias Biológicas, CENUR Litoral Norte, Universidad de La República, 60000, Paysandú, Uruguay. guzmanalvarezlqo@gmail.com.
  • van Pul L; Department of Experimental Immunology, Amsterdam UMC, Amsterdam Infection & Immunity Institute, University of Amsterdam, 1105 AZ, Amsterdam, the Netherlands.
  • Robert X; Retroviruses and Structural Biochemistry, UMR5086, Université de Lyon, CNRS, MMSB, 69367, Lyon, France.
  • Artía Z; Laboratorio de Moléculas Bioactivas, Departamento de Ciencias Biológicas, CENUR Litoral Norte, Universidad de La República, 60000, Paysandú, Uruguay.
  • van Nuenen AC; Department of Experimental Immunology, Amsterdam UMC, Amsterdam Infection & Immunity Institute, University of Amsterdam, 1105 AZ, Amsterdam, the Netherlands.
  • Long M; Retroviruses and Structural Biochemistry, UMR5086, Université de Lyon, CNRS, MMSB, 69367, Lyon, France.
  • Sierra N; Laboratorio de Moléculas Bioactivas, Departamento de Ciencias Biológicas, CENUR Litoral Norte, Universidad de La República, 60000, Paysandú, Uruguay.
  • Porcal W; Departamento de Química Orgánica, Facultad de Química, Universidad de La República, 11800, Montevideo, Uruguay.
  • Kootstra NA; Department of Experimental Immunology, Amsterdam UMC, Amsterdam Infection & Immunity Institute, University of Amsterdam, 1105 AZ, Amsterdam, the Netherlands. n.a.kootstra@amsterdamumc.nl.
  • Guillon C; Retroviruses and Structural Biochemistry, UMR5086, Université de Lyon, CNRS, MMSB, 69367, Lyon, France. christophe.guillon@ibcp.fr.
BMC Pharmacol Toxicol ; 23(1): 43, 2022 06 28.
Article in En | MEDLINE | ID: mdl-35765101
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Full text: 1 Collection: 01-internacional Database: MEDLINE Main subject: HIV Infections / HIV-1 Type of study: Diagnostic_studies Limits: Humans Language: En Journal: BMC Pharmacol Toxicol Year: 2022 Document type: Article Affiliation country: Uruguay Country of publication: United kingdom
Fulltext
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Full text: 1 Collection: 01-internacional Database: MEDLINE Main subject: HIV Infections / HIV-1 Type of study: Diagnostic_studies Limits: Humans Language: En Journal: BMC Pharmacol Toxicol Year: 2022 Document type: Article Affiliation country: Uruguay Country of publication: United kingdom