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Mini kidney organoids deliver maximal drug screening impact.
Dixon, Eryn E; Bradford, Shayna T J; Humphreys, Benjamin D.
Affiliation
  • Dixon EE; Division of Nephrology, Department of Medicine, Washington University in St. Louis, St. Louis, MO, USA.
  • Bradford STJ; Division of Nephrology, Department of Medicine, Washington University in St. Louis, St. Louis, MO, USA.
  • Humphreys BD; Division of Nephrology, Department of Medicine, Washington University in St. Louis, St. Louis, MO, USA; Department of Developmental Biology, Washington University in St. Louis, St. Louis, MO, USA. Electronic address: humphreysbd@wustl.edu.
Cell Stem Cell ; 29(7): 1011-1012, 2022 07 07.
Article in En | MEDLINE | ID: mdl-35803221
ABSTRACT
In this issue of Cell Stem Cell, Tran and colleagues develop a platform for differentiating thousands of miniature kidney organoids consisting of one or two nephron-like structures each. They use this platform to identify a potent new inhibitor of cyst growth in organoid models of autosomal-dominant polycystic kidney disease.
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Full text: 1 Collection: 01-internacional Database: MEDLINE Main subject: Organoids / Kidney Type of study: Diagnostic_studies / Screening_studies Language: En Journal: Cell Stem Cell Year: 2022 Document type: Article Affiliation country: United States
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Full text: 1 Collection: 01-internacional Database: MEDLINE Main subject: Organoids / Kidney Type of study: Diagnostic_studies / Screening_studies Language: En Journal: Cell Stem Cell Year: 2022 Document type: Article Affiliation country: United States