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Germacranolide- and guaianolide-type sesquiterpenoids from Achillea alpina L. reduce insulin resistance in palmitic acid-treated HepG2 cells via inhibition of the NLRP3 inflammasome pathway.
Xue, Gui-Min; Zhao, Chen-Guang; Xue, Jin-Feng; Du, Kun; Duan, Jiang-Jing; Pan, Hao; Li, Meng; Chen, Hui; Sun, Yan-Jun; Feng, Wei-Sheng; Ma, Ting; Zhang, Wen-Da.
Affiliation
  • Xue GM; College of Pharmacy, Henan University of Chinese Medicine, Zhengzhou, 450046, China. Electronic address: xueguimin123@126.com.
  • Zhao CG; College of Pharmacy, Henan University of Chinese Medicine, Zhengzhou, 450046, China.
  • Xue JF; College of Pharmacy, Henan University of Chinese Medicine, Zhengzhou, 450046, China.
  • Du K; College of Pharmacy, Henan University of Chinese Medicine, Zhengzhou, 450046, China.
  • Duan JJ; College of Pharmacy, Henan University of Chinese Medicine, Zhengzhou, 450046, China.
  • Pan H; College of Pharmacy, Henan University of Chinese Medicine, Zhengzhou, 450046, China.
  • Li M; College of Pharmacy, Henan University of Chinese Medicine, Zhengzhou, 450046, China.
  • Chen H; College of Pharmacy, Henan University of Chinese Medicine, Zhengzhou, 450046, China.
  • Sun YJ; College of Pharmacy, Henan University of Chinese Medicine, Zhengzhou, 450046, China.
  • Feng WS; College of Pharmacy, Henan University of Chinese Medicine, Zhengzhou, 450046, China.
  • Ma T; School of Pharmaceutical Sciences, Key Laboratory of Advanced Drug Preparation Technologies, Ministry of Education, Zhengzhou University, Zhengzhou, 450001, China.
  • Zhang WD; Department of Pharmacy, Henan Key Laboratory for Precision Clinical Pharmacy, The First Affiliated Hospital of Zhengzhou University, No. 1, East Jianshe Road, Zhengzhou, 450052, China. Electronic address: zhangwenda16@126.com.
Phytochemistry ; 202: 113297, 2022 Oct.
Article in En | MEDLINE | ID: mdl-35803306
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Full text: 1 Collection: 01-internacional Database: MEDLINE Main subject: Sesquiterpenes / Insulin Resistance / Achillea Limits: Humans Language: En Journal: Phytochemistry Year: 2022 Document type: Article Country of publication: United kingdom
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Full text: 1 Collection: 01-internacional Database: MEDLINE Main subject: Sesquiterpenes / Insulin Resistance / Achillea Limits: Humans Language: En Journal: Phytochemistry Year: 2022 Document type: Article Country of publication: United kingdom