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Therapeutic targeting of PD-1/PD-L1 blockade by novel small-molecule inhibitors recruits cytotoxic T cells into solid tumor microenvironment.
Acúrcio, Rita C; Pozzi, Sabina; Carreira, Barbara; Pojo, Marta; Gómez-Cebrián, Nuria; Casimiro, Sandra; Fernandes, Adelaide; Barateiro, Andreia; Farricha, Vitor; Brito, Joaquim; Leandro, Ana Paula; Salvador, Jorge A R; Graça, Luís; Puchades-Carrasco, Leonor; Costa, Luís; Satchi-Fainaro, Ronit; Guedes, Rita C; Florindo, Helena F.
Affiliation
  • Acúrcio RC; Research Institute for Medicines (iMed.ULisboa), Faculty of Pharmacy, Universidade de Lisboa, 1649-003 Lisbon, Portugal.
  • Pozzi S; Department of Physiology and Pharmacology, Sackler Faculty of Medicine, Tel Aviv University, Tel Aviv 6997801, Israel.
  • Carreira B; Research Institute for Medicines (iMed.ULisboa), Faculty of Pharmacy, Universidade de Lisboa, 1649-003 Lisbon, Portugal.
  • Pojo M; Unidade de Investigação em Patobiologia Molecular (UIPM) do Instituto Português de Oncologia de Lisboa Francisco Gentil EPE 1099-023, Lisbon, Portugal.
  • Gómez-Cebrián N; Instituto de Investigación Sanitaria La Fe, 46026 Valencia, Spain.
  • Casimiro S; Instituto de Medicina Molecular - João Lobo Antunes, Faculdade de Medicina, Universidade de Lisboa, 1649-028 Lisbon, Portugal.
  • Fernandes A; Research Institute for Medicines (iMed.ULisboa), Faculty of Pharmacy, Universidade de Lisboa, 1649-003 Lisbon, Portugal.
  • Barateiro A; Research Institute for Medicines (iMed.ULisboa), Faculty of Pharmacy, Universidade de Lisboa, 1649-003 Lisbon, Portugal.
  • Farricha V; Serviço de Cirurgia do Instituto Português de Oncologia de Lisboa Francisco Gentil EPE, 1099-023 Lisbon, Portugal.
  • Brito J; Serviço de Ortopedia, Centro Hospitalar Universitário Lisboa Norte, 1649-028 Lisbon, Portugal.
  • Leandro AP; Research Institute for Medicines (iMed.ULisboa), Faculty of Pharmacy, Universidade de Lisboa, 1649-003 Lisbon, Portugal.
  • Salvador JAR; Laboratory of Pharmaceutical Chemistry, Faculty of Pharmacy, University of Coimbra,Centre for Neuroscience and Cell Biology, 3000-548 Coimbra, Portugal.
  • Graça L; Instituto de Medicina Molecular - João Lobo Antunes, Faculdade de Medicina, Universidade de Lisboa, 1649-028 Lisbon, Portugal.
  • Puchades-Carrasco L; Instituto de Investigación Sanitaria La Fe, 46026 Valencia, Spain.
  • Costa L; Instituto de Medicina Molecular - João Lobo Antunes, Faculdade de Medicina, Universidade de Lisboa, 1649-028 Lisbon, Portugal.
  • Satchi-Fainaro R; Serviço de Oncologia Médica, Centro Hospitalar Universitário Lisboa Norte, 1649-028, Lisbon, Portugal.
  • Guedes RC; Department of Physiology and Pharmacology, Sackler Faculty of Medicine, Tel Aviv University, Tel Aviv 6997801, Israel hflorindo@ff.ulisboa.pt rguedes@ff.ulisboa.pt ronitsf@tauex.tau.ac.il.
  • Florindo HF; Sagol School of Neurosciences, Tel Aviv University, Tel Aviv 6997801, Israel.
J Immunother Cancer ; 10(7)2022 07.
Article in En | MEDLINE | ID: mdl-35863821
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Full text: 1 Collection: 01-internacional Database: MEDLINE Main subject: Programmed Cell Death 1 Receptor / Neoplasms Limits: Humans Language: En Journal: J Immunother Cancer Year: 2022 Document type: Article Affiliation country: Portugal Country of publication: United kingdom
Fulltext
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Full text: 1 Collection: 01-internacional Database: MEDLINE Main subject: Programmed Cell Death 1 Receptor / Neoplasms Limits: Humans Language: En Journal: J Immunother Cancer Year: 2022 Document type: Article Affiliation country: Portugal Country of publication: United kingdom