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Metabolic rescue ameliorates mitochondrial encephalo-cardiomyopathy in murine and human iPSC models of Leigh syndrome.
Yoon, Jin-Young; Daneshgar, Nastaran; Chu, Yi; Chen, Biyi; Hefti, Marco; Vikram, Ajit; Irani, Kaikobad; Song, Long-Sheng; Brenner, Charles; Abel, E Dale; London, Barry; Dai, Dao-Fu.
Affiliation
  • Yoon JY; Division of Cardiovascular Medicine, Department of Internal Medicine, University of Iowa Carver College of Medicine, Iowa City, Iowa, USA.
  • Daneshgar N; Abboud Cardiovascular Research Center, University of Iowa Carver College of Medicine, Iowa City, Iowa, USA.
  • Chu Y; Department of Pathology, Carver College of Medicine, University of Iowa, Iowa City, Iowa, USA.
  • Chen B; Department of Pathology, Carver College of Medicine, University of Iowa, Iowa City, Iowa, USA.
  • Hefti M; Division of Cardiovascular Medicine, Department of Internal Medicine, University of Iowa Carver College of Medicine, Iowa City, Iowa, USA.
  • Vikram A; Abboud Cardiovascular Research Center, University of Iowa Carver College of Medicine, Iowa City, Iowa, USA.
  • Irani K; Department of Pathology, Carver College of Medicine, University of Iowa, Iowa City, Iowa, USA.
  • Song LS; Division of Cardiovascular Medicine, Department of Internal Medicine, University of Iowa Carver College of Medicine, Iowa City, Iowa, USA.
  • Brenner C; Division of Cardiovascular Medicine, Department of Internal Medicine, University of Iowa Carver College of Medicine, Iowa City, Iowa, USA.
  • Abel ED; Abboud Cardiovascular Research Center, University of Iowa Carver College of Medicine, Iowa City, Iowa, USA.
  • London B; Division of Cardiovascular Medicine, Department of Internal Medicine, University of Iowa Carver College of Medicine, Iowa City, Iowa, USA.
  • Dai DF; Abboud Cardiovascular Research Center, University of Iowa Carver College of Medicine, Iowa City, Iowa, USA.
Clin Transl Med ; 12(7): e954, 2022 07.
Article in En | MEDLINE | ID: mdl-35872650
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Full text: 1 Collection: 01-internacional Database: MEDLINE Main subject: Leigh Disease / Induced Pluripotent Stem Cells / Cardiomyopathies Limits: Animals / Humans Language: En Journal: Clin Transl Med Year: 2022 Document type: Article Affiliation country: United States Country of publication: United States
Fulltext
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Full text: 1 Collection: 01-internacional Database: MEDLINE Main subject: Leigh Disease / Induced Pluripotent Stem Cells / Cardiomyopathies Limits: Animals / Humans Language: En Journal: Clin Transl Med Year: 2022 Document type: Article Affiliation country: United States Country of publication: United States