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Polygenic resilience scores capture protective genetic effects for Alzheimer's disease.
Hou, Jiahui; Hess, Jonathan L; Armstrong, Nicola; Bis, Joshua C; Grenier-Boley, Benjamin; Karlsson, Ida K; Leonenko, Ganna; Numbers, Katya; O'Brien, Eleanor K; Shadrin, Alexey; Thalamuthu, Anbupalam; Yang, Qiong; Andreassen, Ole A; Brodaty, Henry; Gatz, Margaret; Kochan, Nicole A; Lambert, Jean-Charles; Laws, Simon M; Masters, Colin L; Mather, Karen A; Pedersen, Nancy L; Posthuma, Danielle; Sachdev, Perminder S; Williams, Julie; Fan, Chun Chieh; Faraone, Stephen V; Fennema-Notestine, Christine; Lin, Shu-Ju; Escott-Price, Valentina; Holmans, Peter; Seshadri, Sudha; Tsuang, Ming T; Kremen, William S; Glatt, Stephen J.
Affiliation
  • Hou J; Psychiatric Genetic Epidemiology & Neurobiology Laboratory (PsychGENe Lab), SUNY Upstate Medical University, Syracuse, NY, USA.
  • Hess JL; Department of Psychiatry and Behavioral Sciences, SUNY Upstate Medical University, Syracuse, NY, USA.
  • Armstrong N; Department of Neuroscience and Physiology, SUNY Upstate Medical University, Syracuse, NY, USA.
  • Bis JC; Psychiatric Genetic Epidemiology & Neurobiology Laboratory (PsychGENe Lab), SUNY Upstate Medical University, Syracuse, NY, USA.
  • Grenier-Boley B; Department of Psychiatry and Behavioral Sciences, SUNY Upstate Medical University, Syracuse, NY, USA.
  • Karlsson IK; Department of Neuroscience and Physiology, SUNY Upstate Medical University, Syracuse, NY, USA.
  • Leonenko G; Mathematics and Statistics, Curtin University, Perth, WA, Australia.
  • Numbers K; Department of Medicine, Cardiovascular Health Research Unit, University of Washington, Seattle, WA, USA.
  • O'Brien EK; U1167-RID-AGE - Facteurs de risque et déterminants moléculaires des maladies liées au vieillissement, Univ. Lille, Inserm, CHU Lille, Institut Pasteur Lille, F-59000, Lille, France.
  • Shadrin A; Department of Medical Epidemiology and Biostatistics, Karolinska Institutet, Stockholm, Sweden.
  • Thalamuthu A; Aging Research Network - Jönköping (ARN-J), School of Health and Welfare, Jönköping University, Jönköping, Sweden.
  • Yang Q; Dementia Research Institute, School of Medicine, Cardiff University, Cardiff, UK.
  • Andreassen OA; Centre for Healthy Brain Ageing (CHeBA), Discipline of Psychiatry and Mental Health, Faculty of Medicine, University of New South Wales, Sydney, NSW, Australia.
  • Brodaty H; Centre for Precision Health, Edith Cowan University, Joondalup, WA, Australia.
  • Gatz M; Collaborative Genomics and Translation Group, School of Medical and Health Sciences, Edith Cowan University, Joondalup, WA, Australia.
  • Kochan NA; NORMENT Centre, Division of Mental Health and Addiction, Oslo University Hospital & Institute of Clinical Medicine, University of Oslo, Oslo, Norway.
  • Lambert JC; Centre for Healthy Brain Ageing (CHeBA), Discipline of Psychiatry and Mental Health, Faculty of Medicine, University of New South Wales, Sydney, NSW, Australia.
  • Laws SM; Department of Biostatistics, School of Public Health, Boston University, Boston, MA, USA.
  • Masters CL; NORMENT Centre, Division of Mental Health and Addiction, Oslo University Hospital & Institute of Clinical Medicine, University of Oslo, Oslo, Norway.
  • Mather KA; Centre for Healthy Brain Ageing (CHeBA), Discipline of Psychiatry and Mental Health, Faculty of Medicine, University of New South Wales, Sydney, NSW, Australia.
  • Pedersen NL; Department of Medical Epidemiology and Biostatistics, Karolinska Institutet, Stockholm, Sweden.
  • Posthuma D; Center for Economic and Social Research, University of Southern California, Los Angeles, CA, USA.
  • Sachdev PS; Centre for Healthy Brain Ageing (CHeBA), Discipline of Psychiatry and Mental Health, Faculty of Medicine, University of New South Wales, Sydney, NSW, Australia.
  • Williams J; U1167-RID-AGE - Facteurs de risque et déterminants moléculaires des maladies liées au vieillissement, Univ. Lille, Inserm, CHU Lille, Institut Pasteur Lille, F-59000, Lille, France.
  • Fan CC; Collaborative Genomics and Translation Group, School of Medical and Health Sciences, Edith Cowan University, Joondalup, WA, Australia.
  • Faraone SV; The Florey Institute, The University of Melbourne, Melbourne, VIC, Australia.
  • Fennema-Notestine C; Centre for Healthy Brain Ageing (CHeBA), Discipline of Psychiatry and Mental Health, Faculty of Medicine, University of New South Wales, Sydney, NSW, Australia.
  • Lin SJ; Neuroscience Research Australia, Randwick, NSW, Australia.
  • Escott-Price V; Department of Medical Epidemiology and Biostatistics, Karolinska Institutet, Stockholm, Sweden.
  • Holmans P; Department of Complex Trait Genetics, Center for Neurogenomics and Cognitive Research, Amsterdam Neuroscience, Vrije Universiteit, Amsterdam, the Netherlands.
  • Seshadri S; Centre for Healthy Brain Ageing (CHeBA), Discipline of Psychiatry and Mental Health, Faculty of Medicine, University of New South Wales, Sydney, NSW, Australia.
  • Tsuang MT; Division of Psychological Medicine and Clinical Neurology and Medical Research Council (MRC) Centre for Neuropsychiatric Genetics and Genomics, School of Medicine, Cardiff University, Cardiff, UK.
  • Glatt SJ; Department of Cognitive Science, University of California San Diego, La Jolla, CA, USA.
Transl Psychiatry ; 12(1): 296, 2022 07 25.
Article in En | MEDLINE | ID: mdl-35879306
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Full text: 1 Collection: 01-internacional Database: MEDLINE Main subject: Alzheimer Disease Type of study: Etiology_studies / Prognostic_studies / Risk_factors_studies Aspects: Patient_preference Limits: Humans Language: En Journal: Transl Psychiatry Year: 2022 Document type: Article Affiliation country: United States Country of publication: United States
Fulltext
Add to My VHL
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Full text: 1 Collection: 01-internacional Database: MEDLINE Main subject: Alzheimer Disease Type of study: Etiology_studies / Prognostic_studies / Risk_factors_studies Aspects: Patient_preference Limits: Humans Language: En Journal: Transl Psychiatry Year: 2022 Document type: Article Affiliation country: United States Country of publication: United States