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Neurovascular dysfunction in GRN-associated frontotemporal dementia identified by single-nucleus RNA sequencing of human cerebral cortex.
Gerrits, Emma; Giannini, Lucia A A; Brouwer, Nieske; Melhem, Shamiram; Seilhean, Danielle; Le Ber, Isabelle; Kamermans, Alwin; Kooij, Gijs; de Vries, Helga E; Boddeke, Erik W G M; Seelaar, Harro; van Swieten, John C; Eggen, Bart J L.
Affiliation
  • Gerrits E; Department of Biomedical Sciences of Cells & Systems, Section of Molecular Neurobiology, University of Groningen and University Medical Center Groningen, Groningen, Netherlands.
  • Giannini LAA; Department of Neurology & Alzheimer Center, Erasmus University Medical Center, Rotterdam, Netherlands.
  • Brouwer N; Department of Biomedical Sciences of Cells & Systems, Section of Molecular Neurobiology, University of Groningen and University Medical Center Groningen, Groningen, Netherlands.
  • Melhem S; Department of Neurology & Alzheimer Center, Erasmus University Medical Center, Rotterdam, Netherlands.
  • Seilhean D; Department of Neuropathology, Pitie Salpetriere Hospital, AP-HP Sorbonne Université, Paris, France.
  • Le Ber I; Paris Brain Institute - Institut du Cerveau (ICM), Sorbonne Université, Inserm U1127, CNRS UMR 7225, AP-HP - Hôpital Pitié-Salpêtrière, Paris, France.
  • Kamermans A; Reference Center for Rare or Early Dementias, IM2A, Département de Neurologie, AP-HP - Hôpital Pitié-Salpêtrière, Paris, France.
  • de Vries HE; MS Center Amsterdam, Department of Molecular Cell Biology and Immunology, Amsterdam Neuroscience, Vrije Universiteit Amsterdam, Amsterdam UMC, Amsterdam, Netherlands.
  • Boddeke EWGM; MS Center Amsterdam, Department of Molecular Cell Biology and Immunology, Amsterdam Neuroscience, Vrije Universiteit Amsterdam, Amsterdam UMC, Amsterdam, Netherlands.
  • Seelaar H; MS Center Amsterdam, Department of Molecular Cell Biology and Immunology, Amsterdam Neuroscience, Vrije Universiteit Amsterdam, Amsterdam UMC, Amsterdam, Netherlands.
  • van Swieten JC; Department of Biomedical Sciences of Cells & Systems, Section of Molecular Neurobiology, University of Groningen and University Medical Center Groningen, Groningen, Netherlands.
  • Eggen BJL; Center for Healthy Ageing, Department of Cellular and Molecular Medicine, University of Copenhagen, Copenhagen, Denmark.
Nat Neurosci ; 25(8): 1034-1048, 2022 08.
Article in En | MEDLINE | ID: mdl-35879464
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Full text: 1 Collection: 01-internacional Database: MEDLINE Main subject: Frontotemporal Dementia / Progranulins Type of study: Prognostic_studies / Risk_factors_studies Limits: Humans Language: En Journal: Nat Neurosci Journal subject: NEUROLOGIA Year: 2022 Document type: Article Affiliation country: Netherlands
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Full text: 1 Collection: 01-internacional Database: MEDLINE Main subject: Frontotemporal Dementia / Progranulins Type of study: Prognostic_studies / Risk_factors_studies Limits: Humans Language: En Journal: Nat Neurosci Journal subject: NEUROLOGIA Year: 2022 Document type: Article Affiliation country: Netherlands