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A highly efficacious live attenuated mumps virus-based SARS-CoV-2 vaccine candidate expressing a six-proline stabilized prefusion spike.
Zhang, Yuexiu; Lu, Mijia; Mahesh, K C; Kim, Eunsoo; Shamseldin, Mohamed M; Ye, Chengjin; Dravid, Piyush; Chamblee, Michelle; Park, Jun-Gyu; Hall, Jesse M; Trivedi, Sheetal; Chaiwatpongsakorn, Supranee; Kenny, Adam D; Murthy, Satyapramod Srinivasa; Sharma, Himanshu; Liang, Xueya; Yount, Jacob S; Kapoor, Amit; Martinez-Sobrido, Luis; Dubey, Purnima; Boyaka, Prosper N; Peeples, Mark E; Li, Jianrong.
Affiliation
  • Zhang Y; Department of Veterinary Biosciences, The Ohio State University, Columbus, OH 43210.
  • Lu M; Department of Veterinary Biosciences, The Ohio State University, Columbus, OH 43210.
  • Mahesh KC; Center for Vaccines and Immunity, Abigail Wexner Research Institute, Nationwide Children's Hospital, Columbus, OH 43205.
  • Kim E; Department of Veterinary Biosciences, The Ohio State University, Columbus, OH 43210.
  • Shamseldin MM; Department of Microbial Infection and Immunity, College of Medicine, The Ohio State University, Columbus, OH 43210.
  • Ye C; Department of Disease Intervention and Prevention, Texas Biomedical Research Institute, San Antonio, TX 78227.
  • Dravid P; Center for Vaccines and Immunity, Abigail Wexner Research Institute, Nationwide Children's Hospital, Columbus, OH 43205.
  • Chamblee M; Department of Veterinary Biosciences, The Ohio State University, Columbus, OH 43210.
  • Park JG; Department of Disease Intervention and Prevention, Texas Biomedical Research Institute, San Antonio, TX 78227.
  • Hall JM; Department of Microbial Infection and Immunity, College of Medicine, The Ohio State University, Columbus, OH 43210.
  • Trivedi S; Center for Vaccines and Immunity, Abigail Wexner Research Institute, Nationwide Children's Hospital, Columbus, OH 43205.
  • Chaiwatpongsakorn S; Center for Vaccines and Immunity, Abigail Wexner Research Institute, Nationwide Children's Hospital, Columbus, OH 43205.
  • Kenny AD; Department of Microbial Infection and Immunity, College of Medicine, The Ohio State University, Columbus, OH 43210.
  • Murthy SS; Center for Vaccines and Immunity, Abigail Wexner Research Institute, Nationwide Children's Hospital, Columbus, OH 43205.
  • Sharma H; Center for Vaccines and Immunity, Abigail Wexner Research Institute, Nationwide Children's Hospital, Columbus, OH 43205.
  • Liang X; Department of Veterinary Biosciences, The Ohio State University, Columbus, OH 43210.
  • Yount JS; Department of Microbial Infection and Immunity, College of Medicine, The Ohio State University, Columbus, OH 43210.
  • Kapoor A; Infectious Disease Institute, The Ohio State University, Columbus, OH 43210.
  • Martinez-Sobrido L; Center for Vaccines and Immunity, Abigail Wexner Research Institute, Nationwide Children's Hospital, Columbus, OH 43205.
  • Dubey P; Infectious Disease Institute, The Ohio State University, Columbus, OH 43210.
  • Boyaka PN; Department of Pediatrics, College of Medicine, The Ohio State University, Columbus, OH 43210.
  • Peeples ME; Department of Disease Intervention and Prevention, Texas Biomedical Research Institute, San Antonio, TX 78227.
  • Li J; Department of Microbial Infection and Immunity, College of Medicine, The Ohio State University, Columbus, OH 43210.
Proc Natl Acad Sci U S A ; 119(33): e2201616119, 2022 08 16.
Article in En | MEDLINE | ID: mdl-35895717
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Full text: 1 Collection: 01-internacional Database: MEDLINE Main subject: Measles-Mumps-Rubella Vaccine / Spike Glycoprotein, Coronavirus / COVID-19 Vaccines / SARS-CoV-2 / COVID-19 / Vaccine Efficacy Limits: Animals Language: En Journal: Proc Natl Acad Sci U S A Year: 2022 Document type: Article Country of publication: United States
Fulltext
Add to My VHL
Print
XML
PubMed Links
Search on Google

Full text: 1 Collection: 01-internacional Database: MEDLINE Main subject: Measles-Mumps-Rubella Vaccine / Spike Glycoprotein, Coronavirus / COVID-19 Vaccines / SARS-CoV-2 / COVID-19 / Vaccine Efficacy Limits: Animals Language: En Journal: Proc Natl Acad Sci U S A Year: 2022 Document type: Article Country of publication: United States