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PI3K drives the de novo synthesis of coenzyme A from vitamin B5.
Dibble, Christian C; Barritt, Samuel A; Perry, Grace E; Lien, Evan C; Geck, Renee C; DuBois-Coyne, Sarah E; Bartee, David; Zengeya, Thomas T; Cohen, Emily B; Yuan, Min; Hopkins, Benjamin D; Meier, Jordan L; Clohessy, John G; Asara, John M; Cantley, Lewis C; Toker, Alex.
Affiliation
  • Dibble CC; Department of Pathology, Cancer Research Institute, Beth Israel Deaconess Medical Center, Harvard Medical School, Boston, MA, USA. ccdibble@bidmc.harvard.edu.
  • Barritt SA; Department of Pathology, Cancer Research Institute, Beth Israel Deaconess Medical Center, Harvard Medical School, Boston, MA, USA.
  • Perry GE; Department of Pathology, Cancer Research Institute, Beth Israel Deaconess Medical Center, Harvard Medical School, Boston, MA, USA.
  • Lien EC; Department of Pathology, Cancer Research Institute, Beth Israel Deaconess Medical Center, Harvard Medical School, Boston, MA, USA.
  • Geck RC; Department of Pathology, Cancer Research Institute, Beth Israel Deaconess Medical Center, Harvard Medical School, Boston, MA, USA.
  • DuBois-Coyne SE; Department of Pathology, Cancer Research Institute, Beth Israel Deaconess Medical Center, Harvard Medical School, Boston, MA, USA.
  • Bartee D; Chemical Biology Laboratory, National Cancer Institute, Frederick, MD, USA.
  • Zengeya TT; Chemical Biology Laboratory, National Cancer Institute, Frederick, MD, USA.
  • Cohen EB; Department of Pathology, Cancer Research Institute, Beth Israel Deaconess Medical Center, Harvard Medical School, Boston, MA, USA.
  • Yuan M; Mass Spectrometry Core, Department of Medicine, Beth Israel Deaconess Medical Center, Harvard Medical School, Boston, MA, USA.
  • Hopkins BD; Department of Genetics and Genomic Sciences, Tisch Cancer Institute, Icahn School of Medicine at Mount Sinai, New York, NY, USA.
  • Meier JL; Chemical Biology Laboratory, National Cancer Institute, Frederick, MD, USA.
  • Clohessy JG; Preclinical Murine Pharmacogenetics Facility and Mouse Hospital, Department of Medicine, Beth Israel Deaconess Medical Center, Boston, MA, USA.
  • Asara JM; Mass Spectrometry Core, Department of Medicine, Beth Israel Deaconess Medical Center, Harvard Medical School, Boston, MA, USA.
  • Cantley LC; The Sandra and Edward Meyer Cancer Center, Weill Medical College of Cornell University, New York, NY, USA.
  • Toker A; Department of Pathology, Cancer Research Institute, Beth Israel Deaconess Medical Center, Harvard Medical School, Boston, MA, USA. atoker@bidmc.harvard.edu.
Nature ; 608(7921): 192-198, 2022 08.
Article in En | MEDLINE | ID: mdl-35896750
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Full text: 1 Collection: 01-internacional Database: MEDLINE Main subject: Pantothenic Acid / Coenzyme A / Phosphatidylinositol 3-Kinase Type of study: Prognostic_studies Language: En Journal: Nature Year: 2022 Document type: Article Affiliation country: United States Country of publication: United kingdom
Fulltext
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Full text: 1 Collection: 01-internacional Database: MEDLINE Main subject: Pantothenic Acid / Coenzyme A / Phosphatidylinositol 3-Kinase Type of study: Prognostic_studies Language: En Journal: Nature Year: 2022 Document type: Article Affiliation country: United States Country of publication: United kingdom