The Impact of Masticatory Function on Cognitive Impairment in Older Patients: A Population-Based Matched Case-Control Study.
Yonsei Med J
; 63(8): 783-789, 2022 Aug.
Article
in En
| MEDLINE
| ID: mdl-35914761
ABSTRACT
PURPOSE:
The aim of this study was to investigate the association between the changes in masticatory function and cognitive impairment by analyzing longitudinal data of older Korean patients. MATERIALS ANDMETHODS:
Patients aged over 60 years with dental records between 2005 to 2010 (baseline; T1) and 2014 to 2020 (follow-up; T2) were selected in a single medical center. Based on the dementia diagnosis after T2, the cohort was classified into two groups, the dementia group (n=122) and the control group (n=366). Changes in masticatory function were calculated using the total functional tooth unit (T-FTU) in both groups. The incidence of tooth extraction (%) and the subsequent rehabilitation during the observation period were also evaluated.RESULTS:
In the dementia group, T-FTU significantly decreased from T1 to T2 (9.81±2.78 to 9.11±3.16, respectively, p=0.008), while no significant change was observed in the control group. During the mean observation period of 9 years, significantly more teeth were extracted and neglected to be prosthetically restored in the dementia group than in the control group. Regression analysis revealed that the number of missing teeth neglected [odds ratio (OR)=1.195, 95% confidence interval (CI)=1.025-1.393, p=0.023] and previous alcohol consumption (OR=4.445, 95% CI=1.831-1.795, p=0.001) were the most significant risk factors of dementia.CONCLUSION:
There might be a causative relationship between the neglected missing dentition and the onset of dementia.Key words
Full text:
1
Collection:
01-internacional
Database:
MEDLINE
Main subject:
Tooth Loss
/
Dementia
/
Cognitive Dysfunction
Type of study:
Etiology_studies
/
Incidence_studies
/
Observational_studies
/
Risk_factors_studies
Limits:
Aged
/
Humans
/
Middle aged
Language:
En
Journal:
Yonsei Med J
Year:
2022
Document type:
Article