Predictive value of a novel sub-item mortality risk score derived from the Norfolk Quality of Life in Diabetic Neuropathy questionnaire in Romanian participants with diabetes mellitus.
Prim Care Diabetes
; 16(5): 684-691, 2022 10.
Article
in En
| MEDLINE
| ID: mdl-35915012
ABSTRACT
AIMS:
To evaluate whether the Norfolk Quality of Life in Diabetic Neuropathy (QOL-DN) questionnaire and the novel Norfolk Mortality Risk Score (NMRS), comprising Norfolk QOL-DN items, can identify 4-year mortality risk in individuals with diabetes.METHODS:
Of 21,756 adults completing Norfolk QOL-DN in 2012, two groups of surviving and deceased patients were identified in 2016 Group 1, from a county capital and Group 2, from six small cities. NMRS was calculated in Group 1 using the 2012 scores of Norfolk QOL-DN items that discriminate between deceased and surviving participants (p < 0.05) and was subsequently applied to Group 2.RESULTS:
763 participants were included (Group 1 481 [450 surviving, 31 deceased]; Group 2 282 [218 surviving, 64 deceased]). Total Norfolk QOL-DN score was significantly higher (worse) in deceased participants than in survivors in both groups (p ≤ 0.008). Optimal cut-off for the 25-item NMRS was 11.5 in Group 1. Individuals in Groups 1 and 2 with NMRS≥ 11.5 in 2012 had a 4-year mortality risk ratio of 4.24 (95 % confidence interval [CI] 1.65-10.84) and 2.33 (95 % CI 1.33-4.07), respectively, corresponding to 8 and 16 additional deaths/100 persons/4 years (p = 0.001).CONCLUSION:
Norfolk QOL-DN and NMRS can identify individuals with diabetes at risk of 4-year mortality.Key words
Full text:
1
Collection:
01-internacional
Database:
MEDLINE
Main subject:
Surveys and Questionnaires
/
Diabetes Mellitus
Type of study:
Etiology_studies
/
Prognostic_studies
/
Risk_factors_studies
Aspects:
Patient_preference
Limits:
Adult
/
Humans
Country/Region as subject:
Europa
Language:
En
Journal:
Prim Care Diabetes
Journal subject:
ENDOCRINOLOGIA
Year:
2022
Document type:
Article