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Natural-product-inspired design and synthesis of thiolated coenzyme Q analogs as promising agents against Gram-positive bacterial strains: insights into structure-activity relationship, activity profile, mode of action, and molecular docking.
Yildirim, Hatice; Yildiz, Mahmut; Bayrak, Nilüfer; Mataraci-Kara, Emel; Özbek-Çelik, Berna; Otsuka, Masami; Fujita, Mikako; Radwan, Mohamed O; TuYuN, Amaç Fatih.
Affiliation
  • Yildirim H; Department of Chemistry, Engineering Faculty, Istanbul University-Cerrahpasa Avcilar 34320 Istanbul Turkey.
  • Yildiz M; Department of Chemistry, Gebze Technical University Gebze 41400 Kocaeli Turkey.
  • Bayrak N; Department of Chemistry, Engineering Faculty, Istanbul University-Cerrahpasa Avcilar 34320 Istanbul Turkey.
  • Mataraci-Kara E; Department of Pharmaceutical Microbiology, Pharmacy Faculty, Istanbul University Beyazit 34116 Istanbul Turkey.
  • Özbek-Çelik B; Department of Pharmaceutical Microbiology, Pharmacy Faculty, Istanbul University Beyazit 34116 Istanbul Turkey.
  • Otsuka M; Medicinal and Biological Chemistry Science Farm Joint Research Laboratory, Faculty of Life Sciences, Kumamoto University 5-1 Oe-honmachi, Chuo-ku Kumamoto 862-0973 Japan.
  • Fujita M; Department of Drug Discovery, Science Farm Ltd 1-7-30 Kuhonji, Chuo-ku Kumamoto 862-0976 Japan.
  • Radwan MO; Medicinal and Biological Chemistry Science Farm Joint Research Laboratory, Faculty of Life Sciences, Kumamoto University 5-1 Oe-honmachi, Chuo-ku Kumamoto 862-0973 Japan.
  • TuYuN AF; Medicinal and Biological Chemistry Science Farm Joint Research Laboratory, Faculty of Life Sciences, Kumamoto University 5-1 Oe-honmachi, Chuo-ku Kumamoto 862-0973 Japan.
RSC Adv ; 12(32): 20507-20518, 2022 Jul 14.
Article in En | MEDLINE | ID: mdl-35919160
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Full text: 1 Collection: 01-internacional Database: MEDLINE Language: En Journal: RSC Adv Year: 2022 Document type: Article Country of publication: United kingdom
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Full text: 1 Collection: 01-internacional Database: MEDLINE Language: En Journal: RSC Adv Year: 2022 Document type: Article Country of publication: United kingdom