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A simple and sensitive HPLC-FL method for bioanalysis of velpatasvir, a novel hepatitis C virus NS5A inhibitor, in rat plasma: Investigation of factors determining its oral bioavailability.
Choi, Eugene; Han, Dong-Gyun; Park, Jeong-Eun; Lee, Ha-Yeon; Yoo, Jin-Wook; Jung, Yunjin; Song, Im-Sook; Yoon, In-Soo.
Affiliation
  • Choi E; Department of Manufacturing Pharmacy, College of Pharmacy, Pusan National University, Busan 46241, South Korea.
  • Han DG; Department of Manufacturing Pharmacy, College of Pharmacy, Pusan National University, Busan 46241, South Korea.
  • Park JE; New Drug Development Center, Daegu-Gyeongbuk Medical Innovation Foundation, Daegu 41061, South Korea.
  • Lee HY; New Drug Development Center, Daegu-Gyeongbuk Medical Innovation Foundation, Daegu 41061, South Korea.
  • Yoo JW; Department of Manufacturing Pharmacy, College of Pharmacy, Pusan National University, Busan 46241, South Korea.
  • Jung Y; Department of Manufacturing Pharmacy, College of Pharmacy, Pusan National University, Busan 46241, South Korea.
  • Song IS; BK21 FOUR Community-Based Intelligent Novel Drug Discovery Education Unit, Vessel-Organ Interaction Research Center (VOICE), Research Institute of Pharmaceutical Sciences, College of Pharmacy, Kyungpook National University, Daegu 41566, South Korea. Electronic address: isssong@knu.ac.kr.
  • Yoon IS; Department of Manufacturing Pharmacy, College of Pharmacy, Pusan National University, Busan 46241, South Korea. Electronic address: insoo.yoon@pusan.ac.kr.
J Chromatogr B Analyt Technol Biomed Life Sci ; 1208: 123399, 2022 Oct 01.
Article in En | MEDLINE | ID: mdl-35921698
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Full text: 1 Collection: 01-internacional Database: MEDLINE Main subject: Hepacivirus / Hepatitis C, Chronic Type of study: Diagnostic_studies Limits: Animals Language: En Journal: J Chromatogr B Analyt Technol Biomed Life Sci Journal subject: ENGENHARIA BIOMEDICA Year: 2022 Document type: Article Affiliation country: South Korea Country of publication: Netherlands
Fulltext
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Full text: 1 Collection: 01-internacional Database: MEDLINE Main subject: Hepacivirus / Hepatitis C, Chronic Type of study: Diagnostic_studies Limits: Animals Language: En Journal: J Chromatogr B Analyt Technol Biomed Life Sci Journal subject: ENGENHARIA BIOMEDICA Year: 2022 Document type: Article Affiliation country: South Korea Country of publication: Netherlands