Diamond-Blackfan anaemia with iron overload: A serious issue.
Br J Haematol
; 199(2): 171-172, 2022 10.
Article
in En
| MEDLINE
| ID: mdl-35929529
ABSTRACT
Transfusion-dependent Diamond-Blackfan anaemia (DBA) patients rapidly develop iron overload and frequently experience cardiac complications. The report by Lecornec and colleagues offers useful details on indications and the management of deferiprone, a highly efficient chelator in removing excess cardiac iron but associated with a high risk of agranulocytosis in DBA patients. Commentary on Lecornec et al. Agranulocytosis in patients with Diamond-Blackfan anaemia (DBA) treated with deferiprone for post-transfusion iron overload A retrospective study of the French DBA cohort. British Journal of Haematology 2022;199285-288.
Full text:
1
Collection:
01-internacional
Database:
MEDLINE
Main subject:
Iron Overload
/
Anemia, Diamond-Blackfan
/
Agranulocytosis
Type of study:
Observational_studies
/
Risk_factors_studies
Limits:
Humans
Language:
En
Journal:
Br J Haematol
Year:
2022
Document type:
Article
Affiliation country:
Italy