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Chromenopyrimidinone exhibit antitumor effects through inhibition of CAP1 (Adenylyl cyclase-associated protein 1) expression in hepatocellular carcinoma.
Kim, Namjeong; Kim, Sanghwa; Song, Yeonhwa; Choi, Inhee; Lee, Su-Yeon; Kim, Kang Mo; Rhu, Hyung Chul; Lee, Ju Young; Seo, Haeng Ran.
Affiliation
  • Kim N; Advanced Biomedical Research Laboratory, Institut Pasteur Korea, 16, Daewangpangyo-ro 712 Beon-gil, Bundang-gu, Seongnam-si, Gyeonggi-do, 463-400, South Korea.
  • Kim S; Advanced Biomedical Research Laboratory, Institut Pasteur Korea, 16, Daewangpangyo-ro 712 Beon-gil, Bundang-gu, Seongnam-si, Gyeonggi-do, 463-400, South Korea.
  • Song Y; Advanced Biomedical Research Laboratory, Institut Pasteur Korea, 16, Daewangpangyo-ro 712 Beon-gil, Bundang-gu, Seongnam-si, Gyeonggi-do, 463-400, South Korea.
  • Choi I; Medicinal Chemistry, Institut Pasteur Korea, 16, Daewangpangyo-ro 712 Beon-gil, Bundang-gu, Seongnam-si, Gyeonggi-do, 463-400, South Korea.
  • Lee SY; Advanced Biomedical Research Laboratory, Institut Pasteur Korea, 16, Daewangpangyo-ro 712 Beon-gil, Bundang-gu, Seongnam-si, Gyeonggi-do, 463-400, South Korea.
  • Kim KM; Department of Gastroenterology, Asan Liver Center, Asan Medical Center, University of Ulsan College of Medicine, Olympic-ro 43-gil, Songpa-gu, Seoul, 05505, South Korea.
  • Rhu HC; R&D Center, J2H Biotech, Saneop-ro 156 Beon-gil, Gwonseon-gu, Suwon-si, Gyeonggi-do, 16648, Republic of Korea.
  • Lee JY; R&D Center, J2H Biotech, Saneop-ro 156 Beon-gil, Gwonseon-gu, Suwon-si, Gyeonggi-do, 16648, Republic of Korea.
  • Seo HR; Advanced Biomedical Research Laboratory, Institut Pasteur Korea, 16, Daewangpangyo-ro 712 Beon-gil, Bundang-gu, Seongnam-si, Gyeonggi-do, 463-400, South Korea. Electronic address: shr1261@ip-korea.org.
Chem Biol Interact ; 365: 110066, 2022 Sep 25.
Article in En | MEDLINE | ID: mdl-35931200

Full text: 1 Collection: 01-internacional Database: MEDLINE Main subject: Pyrimidinones / Carcinoma, Hepatocellular / Liver Neoplasms / Antineoplastic Agents Type of study: Risk_factors_studies Limits: Humans Language: En Journal: Chem Biol Interact Year: 2022 Document type: Article Affiliation country: South Korea Country of publication: Ireland

Full text: 1 Collection: 01-internacional Database: MEDLINE Main subject: Pyrimidinones / Carcinoma, Hepatocellular / Liver Neoplasms / Antineoplastic Agents Type of study: Risk_factors_studies Limits: Humans Language: En Journal: Chem Biol Interact Year: 2022 Document type: Article Affiliation country: South Korea Country of publication: Ireland