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Crohn's Disease Patients Uniquely Contain Inflammatory Responses to Flagellin in a CD4 Effector Memory Subset.
Morgan, Nadine N; Duck, Lennard W; Wu, Jiongru; Rujani, Mahmud; Thomes, Paul G; Elson, Charles O; Mannon, Peter J.
Affiliation
  • Morgan NN; Program in Immunology, Department of Medicine, University of Alabama at Birmingham, Birmingham, AL, USA.
  • Duck LW; Program in Immunology, Department of Medicine, University of Alabama at Birmingham, Birmingham, AL, USA.
  • Wu J; Division of Gastroenterology and Hepatology, Paustian IBD Center, University of Nebraska Medical Center, Omaha, NE, USA.
  • Rujani M; Medical Service and Department of Medicine, Omaha VA Medical Center, Omaha, NE, USA.
  • Thomes PG; Medical Service and Department of Medicine, Omaha VA Medical Center, Omaha, NE, USA.
  • Elson CO; Division of Gastroenterology and Hepatology, Paustian IBD Center, University of Nebraska Medical Center, Omaha, NE, USA.
  • Mannon PJ; Medical Service and Department of Medicine, Omaha VA Medical Center, Omaha, NE, USA.
Inflamm Bowel Dis ; 28(12): 1893-1903, 2022 12 01.
Article in En | MEDLINE | ID: mdl-35931421
Crohn's disease patients display inflammatory cytokine responses to flagellin antigens in an expanded effector memory CD4 subset that is not seen in ulcerative colitis or non­inflammatory bowel disease control subjects. These cells correlate with levels of the specific cognate anti-flagellin antibodies.
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Full text: 1 Collection: 01-internacional Database: MEDLINE Main subject: Colitis, Ulcerative / Crohn Disease Type of study: Risk_factors_studies Limits: Humans Language: En Journal: Inflamm Bowel Dis Journal subject: GASTROENTEROLOGIA Year: 2022 Document type: Article Affiliation country: United States Country of publication: United kingdom
Fulltext
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Full text: 1 Collection: 01-internacional Database: MEDLINE Main subject: Colitis, Ulcerative / Crohn Disease Type of study: Risk_factors_studies Limits: Humans Language: En Journal: Inflamm Bowel Dis Journal subject: GASTROENTEROLOGIA Year: 2022 Document type: Article Affiliation country: United States Country of publication: United kingdom