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The Future of heart procurement with donation after circulatory death: Current practice and opportunities for advancement.
Ayer, Austin; Schroder, Jacob N; Casalinova, Sarah; Doberne, Julie W; Bryner, Benjamin S; Patel, Chetan B; DeVore, Adam D.
Affiliation
  • Ayer A; Department of Medicine, Duke University School of Medicine, Durham, North Carolina.
  • Schroder JN; Division of Cardiovascular and Thoracic Surgery, Department of Surgery, Duke University Medical Center, Durham, North Carolina.
  • Casalinova S; Division of Cardiovascular and Thoracic Surgery, Department of Surgery, Duke University Medical Center, Durham, North Carolina.
  • Doberne JW; Division of Cardiovascular and Thoracic Surgery, Department of Surgery, Duke University Medical Center, Durham, North Carolina.
  • Bryner BS; Division of Cardiovascular and Thoracic Surgery, Department of Surgery, Duke University Medical Center, Durham, North Carolina.
  • Patel CB; Department of Medicine, Duke University School of Medicine, Durham, North Carolina.
  • DeVore AD; Department of Medicine, Duke University School of Medicine, Durham, North Carolina; Duke Clinical Research Institute, Durham, North Carolina. Electronic address: adam.devore@duke.edu.
J Heart Lung Transplant ; 41(10): 1385-1390, 2022 10.
Article in En | MEDLINE | ID: mdl-35953351
ABSTRACT
Heart Donation after Circulatory Death (DCD) has the potential to significantly increase the number of patients benefitting from heart transplantation. However, the expansion of DCD heart transplantation is currently limited by unanswered questions pertaining to best practices in DCD heart procurement. Additionally, significant variability exists within regulatory frameworks, professional guidelines, and published practices of DCD procurement processes. Here we describe the current practice and outstanding questions related to fundamental aspects of DCD heart procurement, including donor selection, premortem donor intervention, ischemic definitions, confirmation of circulatory death, and techniques for heart procurement and preservation. Addressing these key issues through research and consensus recommendations will facilitate the advancement of the field and ultimately expand the opportunity for heart transplantation to a greater number of patients.
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Full text: 1 Collection: 01-internacional Database: MEDLINE Main subject: Tissue and Organ Procurement / Heart Transplantation Type of study: Guideline Limits: Humans Language: En Journal: J Heart Lung Transplant Journal subject: CARDIOLOGIA / TRANSPLANTE Year: 2022 Document type: Article

Full text: 1 Collection: 01-internacional Database: MEDLINE Main subject: Tissue and Organ Procurement / Heart Transplantation Type of study: Guideline Limits: Humans Language: En Journal: J Heart Lung Transplant Journal subject: CARDIOLOGIA / TRANSPLANTE Year: 2022 Document type: Article