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A Synopsis Clonal Hematopoiesis of Indeterminate Potential in Hematology.
Bou Zerdan, Maroun; Nasr, Lewis; Saba, Ludovic; Meouchy, Paul; Safi, Nadine; Allam, Sabine; Bhandari, Jenish; Chaulagain, Chakra P.
Affiliation
  • Bou Zerdan M; Department of Internal Medicine, SUNY Upstate Medical University, New York, NY 10009, USA.
  • Nasr L; Department of Hematology-Oncology, Myeloma and Amyloidosis Program, Maroone Cancer Center, Cleveland Clinic Florida, Weston, FL 33326, USA.
  • Saba L; Faculty of Medicine, Saint-Joseph University, Beirut P.O. Box 100, Lebanon.
  • Meouchy P; Faculty of Medicine, Saint-Joseph University, Beirut P.O. Box 100, Lebanon.
  • Safi N; Department of Internal Medicine, Division of Hematology and Oncology, Naef K. Basile Cancer Institute, American University of Beirut Medical Center, Beirut P.O. Box 100, Lebanon.
  • Allam S; Department of Internal Medicine, Division of Hematology and Oncology, Naef K. Basile Cancer Institute, American University of Beirut Medical Center, Beirut P.O. Box 100, Lebanon.
  • Bhandari J; Department of Medicine and Medical Sciences, University of Balamand, Balamand P.O. Box 100, Lebanon.
  • Chaulagain CP; Department of Internal Medicine, SUNY Upstate Medical University, New York, NY 10009, USA.
Cancers (Basel) ; 14(15)2022 Jul 28.
Article in En | MEDLINE | ID: mdl-35954328
Clonal hematopoiesis of indeterminate potential can be defined as genetic mutations that correlate in hematologic neoplasia such as myelodysplastic syndrome. Patients with cytopenia increasingly undergo molecular genetic tests of peripheral blood or bone marrow for diagnostic purposes. Recently, a new entity has been demarcated to lessen the risk of incorrect diagnoses of hematologic malignancies. This new entity is a potential precursor of myeloid diseases, analogous to monoclonal gammopathy of undetermined significance as a potential precursor of multiple myeloma.
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Full text: 1 Collection: 01-internacional Database: MEDLINE Language: En Journal: Cancers (Basel) Year: 2022 Document type: Article Affiliation country: United States Country of publication: Switzerland
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Full text: 1 Collection: 01-internacional Database: MEDLINE Language: En Journal: Cancers (Basel) Year: 2022 Document type: Article Affiliation country: United States Country of publication: Switzerland