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Construction of Covalent Bisubstrate Inhibitor of Protein Kinase Reacting with Cysteine Residue at Substrate-Binding Site.
Sõrmus, Tanel; Lavogina, Darja; Teearu, Anu; Enkvist, Erki; Uri, Asko; Viht, Kaido.
Affiliation
  • Sõrmus T; Institute of Chemistry, University of Tartu, 14A Ravila St., 50411 Tartu, Estonia.
  • Lavogina D; Institute of Chemistry, University of Tartu, 14A Ravila St., 50411 Tartu, Estonia.
  • Teearu A; Institute of Chemistry, University of Tartu, 14A Ravila St., 50411 Tartu, Estonia.
  • Enkvist E; Institute of Chemistry, University of Tartu, 14A Ravila St., 50411 Tartu, Estonia.
  • Uri A; Institute of Chemistry, University of Tartu, 14A Ravila St., 50411 Tartu, Estonia.
  • Viht K; Institute of Chemistry, University of Tartu, 14A Ravila St., 50411 Tartu, Estonia.
J Med Chem ; 65(16): 10975-10991, 2022 08 25.
Article in En | MEDLINE | ID: mdl-35960538
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Full text: 1 Collection: 01-internacional Database: MEDLINE Main subject: Protein Kinases / Cysteine Limits: Humans Language: En Journal: J Med Chem Journal subject: QUIMICA Year: 2022 Document type: Article Affiliation country: Estonia Country of publication: United States
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Full text: 1 Collection: 01-internacional Database: MEDLINE Main subject: Protein Kinases / Cysteine Limits: Humans Language: En Journal: J Med Chem Journal subject: QUIMICA Year: 2022 Document type: Article Affiliation country: Estonia Country of publication: United States