Inhibition of the DAPKs-L13a axis prevents a GAIT-like motif-mediated HuR insufficiency in melanoma cells.

Noulet, Fanny; Merat, Rastine

Noulet, Fanny; Merat, Rastine.

Affiliation

Noulet F; Dermato-Oncology Unit, Division of Dermatology, University Hospital of Geneva, Switzerland; Department of Pathology and Immunology, Faculty of Medicine, University of Geneva, Switzerland.
Merat R; Dermato-Oncology Unit, Division of Dermatology, University Hospital of Geneva, Switzerland; Department of Pathology and Immunology, Faculty of Medicine, University of Geneva, Switzerland. Electronic address: rastine.merat@hcuge.ch.

Biochem Biophys Res Commun ; 626: 21-29, 2022 10 20.

Article in En | MEDLINE | ID: mdl-35970041

Subject(s)

Melanoma; Proto-Oncogene Proteins B-raf; 3' Untranslated Regions; ELAV Proteins/genetics; ELAV Proteins/metabolism; ELAV-Like Protein 1/genetics; ELAV-Like Protein 1/metabolism; Humans; Melanoma/drug therapy; Melanoma/genetics; Phosphorylation; Polyadenylation; Proto-Oncogene Proteins B-raf/genetics; Proto-Oncogene Proteins B-raf/metabolism; RNA, Messenger/genetics

Key words

Adaptive resistance; BRAF inhibition; DAPK inhibition; GAIT element; HuR; Melanoma

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Full text: 1 Collection: 01-internacional Database: MEDLINE Main subject: Proto-Oncogene Proteins B-raf / Melanoma Limits: Humans Language: En Journal: Biochem Biophys Res Commun Year: 2022 Document type: Article Affiliation country: Switzerland Country of publication: United States

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