CaMK4 overexpression in polycystic kidney disease promotes mTOR-mediated cell proliferation.

Zhang, Yan; Daniel, Emily A; Metcalf, July; Dai, Yuqiao; Reif, Gail A; Wallace, Darren P

Zhang, Yan; Daniel, Emily A; Metcalf, July; Dai, Yuqiao; Reif, Gail A; Wallace, Darren P.

Affiliation

Zhang Y; Department of Internal Medicine, University of Kansas Medical Center, Kansas City, KS 66160-3018, USA.
Daniel EA; Jared Grantham Kidney Institute, University of Kansas Medical Center, Kansas City, KS 66160-3018, USA.
Metcalf J; Department of Internal Medicine, University of Kansas Medical Center, Kansas City, KS 66160-3018, USA.
Dai Y; Jared Grantham Kidney Institute, University of Kansas Medical Center, Kansas City, KS 66160-3018, USA.
Reif GA; Department of Internal Medicine, University of Kansas Medical Center, Kansas City, KS 66160-3018, USA.
Wallace DP; Jared Grantham Kidney Institute, University of Kansas Medical Center, Kansas City, KS 66160-3018, USA.

J Mol Cell Biol ; 14(7)2022 09 27.

Article in En | MEDLINE | ID: mdl-36002021

Subject(s)

Cysts; Polycystic Kidney Diseases; Polycystic Kidney, Autosomal Dominant; Mice; Animals; Humans; Polycystic Kidney, Autosomal Dominant/metabolism; AMP-Activated Protein Kinases/metabolism; Calcium; Polycystic Kidney Diseases/metabolism; TOR Serine-Threonine Kinases/metabolism; Kidney/metabolism; Cell Proliferation; Mammals; Calcium-Calmodulin-Dependent Protein Kinase Type 4

Key words

ADPKD; AMPK; CaMK4; CaMKKß; LKB1; calmodulin

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Full text: 1 Collection: 01-internacional Database: MEDLINE Main subject: Polycystic Kidney, Autosomal Dominant / Cysts / Polycystic Kidney Diseases Limits: Animals / Humans Language: En Journal: J Mol Cell Biol Journal subject: BIOLOGIA MOLECULAR Year: 2022 Document type: Article Affiliation country: United States Country of publication: United States

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