Omega-3 Fatty Acids for the Management of Osteoarthritis: A Narrative Review.
Nutrients
; 14(16)2022 Aug 16.
Article
in En
| MEDLINE
| ID: mdl-36014868
ABSTRACT
Osteoarthritis (OA) is a disease which results in degeneration of cartilage within joints and affects approximately 13.6% of adults over 20 years of age in Canada and the United States of America. OA is characterized by a state of low-grade inflammation which leads to a greater state of cellular catabolism disrupting the homeostasis of cartilage synthesis and degradation. Omega-3 polyunsaturated fatty acids (PUFAs) have been postulated as a potential therapeutic treatment option for individuals with OA. Omega-3 PUFAs are recognized for their anti-inflammatory properties, which could be beneficial in the context of OA to moderate pro-inflammatory markers and cartilage loss. The purpose of this narrative review is to outline recent pre-clinical and clinical evidence for the use of omega-3 in the management of OA.
Key words
Full text:
1
Collection:
01-internacional
Database:
MEDLINE
Main subject:
Osteoarthritis
/
Fatty Acids, Omega-3
Limits:
Adult
/
Humans
Country/Region as subject:
America do norte
Language:
En
Journal:
Nutrients
Year:
2022
Document type:
Article
Affiliation country:
Canada
Publication country:
CH
/
SUIZA
/
SUÍÇA
/
SWITZERLAND