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Jatavaleridoids A-H, eight new iridoids from the roots and rhizomes of Valeriana jatamansi Jones.
Tang, Jian-Xian; Quan, Li-Qiu; Xie, Kai; Zhou, Yan; Ye, Rui-Rong; Liu, Dan; Li, Rong-Tao; Li, Hong-Mei.
Affiliation
  • Tang JX; Faculty of Life Science and Technology, Kunming University of Science and Technology, Kunming 650500, Yunnan, PR China.
  • Quan LQ; Faculty of Life Science and Technology, Kunming University of Science and Technology, Kunming 650500, Yunnan, PR China.
  • Xie K; Faculty of Life Science and Technology, Kunming University of Science and Technology, Kunming 650500, Yunnan, PR China.
  • Zhou Y; Faculty of Life Science and Technology, Kunming University of Science and Technology, Kunming 650500, Yunnan, PR China.
  • Ye RR; Faculty of Life Science and Technology, Kunming University of Science and Technology, Kunming 650500, Yunnan, PR China.
  • Liu D; Faculty of Life Science and Technology, Kunming University of Science and Technology, Kunming 650500, Yunnan, PR China.
  • Li RT; Faculty of Life Science and Technology, Kunming University of Science and Technology, Kunming 650500, Yunnan, PR China. Electronic address: rongtaolikm@163.com.
  • Li HM; Faculty of Life Science and Technology, Kunming University of Science and Technology, Kunming 650500, Yunnan, PR China. Electronic address: lihongmei0823@163.com.
Fitoterapia ; 162: 105286, 2022 Oct.
Article in En | MEDLINE | ID: mdl-36029942
Eight new iridoids, jatavaleridoids A-H (1-8), were isolated from the roots and rhizomes of Valeriana jatamansi. Their structures and absolute configurations were elucidated based on NMR and HRESIMS spectroscopic data, as well as quantum chemical calculation. Structurally, compounds 1-5 and 8 were rare iridoids with long-chain fatty acid esters at C-10. In addition, compound 7 showed cytotoxicity, while compounds 1 and 2 exhibited inhibition on NO production.
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Full text: 1 Collection: 01-internacional Database: MEDLINE Main subject: Valerian / Nardostachys Language: En Journal: Fitoterapia Year: 2022 Document type: Article Country of publication: Netherlands
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Full text: 1 Collection: 01-internacional Database: MEDLINE Main subject: Valerian / Nardostachys Language: En Journal: Fitoterapia Year: 2022 Document type: Article Country of publication: Netherlands