RAI16 maintains intestinal homeostasis and inhibits NLRP3-dependent IL-18/CXCL16-induced colitis and the progression of colitis-associated colorectal cancer.

Wang, Wen; Ding, Cui-Ling; Wu, Meng-Xue; Guo, Wen; Hu, Ran; Liu, Yan; Qi, Zhong-Tian; Jia, Xin-Ming

Wang, Wen; Ding, Cui-Ling; Wu, Meng-Xue; Guo, Wen; Hu, Ran; Liu, Yan; Qi, Zhong-Tian; Jia, Xin-Ming.

Affiliation

Wang W; Clinical Medicine Scientific and Technical Innovation Center, Shanghai Tenth People's Hospital, Tongji University School of Medicine, Shanghai, China.
Ding CL; Department of Biodefence, Naval Medical University, Shanghai, China.
Wu MX; Clinical Medicine Scientific and Technical Innovation Center, Shanghai Tenth People's Hospital, Tongji University School of Medicine, Shanghai, China.
Guo W; Clinical Medicine Scientific and Technical Innovation Center, Shanghai Tenth People's Hospital, Tongji University School of Medicine, Shanghai, China.
Hu R; Clinical Medicine Scientific and Technical Innovation Center, Shanghai Tenth People's Hospital, Tongji University School of Medicine, Shanghai, China.
Liu Y; Department of Biodefence, Naval Medical University, Shanghai, China.
Qi ZT; Department of Biodefence, Naval Medical University, Shanghai, China.
Jia XM; Clinical Medicine Scientific and Technical Innovation Center, Shanghai Tenth People's Hospital, Tongji University School of Medicine, Shanghai, China.

Clin Transl Med ; 12(8): e993, 2022 08.

Article in En | MEDLINE | ID: mdl-36030497

Subject(s)

Colitis-Associated Neoplasms; Colitis; Chemokine CXCL16; Homeostasis; Humans; Interleukin-18; NLR Family, Pyrin Domain-Containing 3 Protein

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Full text: 1 Collection: 01-internacional Database: MEDLINE Main subject: Colitis / Colitis-Associated Neoplasms Type of study: Risk_factors_studies Limits: Humans Language: En Journal: Clin Transl Med Year: 2022 Document type: Article Affiliation country: China

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