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Small molecule mediated inhibition of protein cargo recognition by peroxisomal transport receptor PEX5 is toxic to Trypanosoma.
Napolitano, Valeria; Softley, Charlotte A; Blat, Artur; Kalel, Vishal C; Schorpp, Kenji; Siebenmorgen, Till; Hadian, Kamyar; Erdmann, Ralf; Sattler, Michael; Popowicz, Grzegorz M; Dubin, Grzegorz.
Affiliation
  • Napolitano V; Malopolska Centre of Biotechnology, Jagiellonian University, Gronostajowa 7a, 30-387, Kraków, Poland. valeria.napolitano@helmholtz-muenchen.de.
  • Softley CA; Faculty of Biochemistry, Biophysics and Biotechnology, Jagiellonian University, Gronostajowa 7, 30-387, Kraków, Poland. valeria.napolitano@helmholtz-muenchen.de.
  • Blat A; Institute of Structural Biology, Helmholtz Zentrum München, Ingolstädter Landstraße 1, 85764, Neuherberg, Germany.
  • Kalel VC; Bavarian NMR Center, Chemistry Department, Technical University of Munich, Garching, 85748, Munich, Germany.
  • Schorpp K; Malopolska Centre of Biotechnology, Jagiellonian University, Gronostajowa 7a, 30-387, Kraków, Poland.
  • Siebenmorgen T; Faculty of Biochemistry, Biophysics and Biotechnology, Jagiellonian University, Gronostajowa 7, 30-387, Kraków, Poland.
  • Hadian K; Institute of Biochemistry and Pathobiochemistry, Department of Systems Biochemistry, Faculty of Medicine, Ruhr University Bochum, 44801, Bochum, Germany.
  • Erdmann R; Institute of Molecular Toxicology and Pharmacology, Helmholtz Zentrum München, Ingolstädter Landstrasse 1, 85764, Neuherberg, Germany.
  • Sattler M; Institute of Structural Biology, Helmholtz Zentrum München, Ingolstädter Landstraße 1, 85764, Neuherberg, Germany.
  • Popowicz GM; Bavarian NMR Center, Chemistry Department, Technical University of Munich, Garching, 85748, Munich, Germany.
  • Dubin G; Institute of Molecular Toxicology and Pharmacology, Helmholtz Zentrum München, Ingolstädter Landstrasse 1, 85764, Neuherberg, Germany.
Sci Rep ; 12(1): 14705, 2022 08 29.
Article in En | MEDLINE | ID: mdl-36038611
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Full text: 1 Collection: 01-internacional Database: MEDLINE Main subject: Trypanosoma / Receptors, Cytoplasmic and Nuclear Type of study: Prognostic_studies Limits: Humans Language: En Journal: Sci Rep Year: 2022 Document type: Article Affiliation country: Poland Country of publication: United kingdom
Fulltext
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Full text: 1 Collection: 01-internacional Database: MEDLINE Main subject: Trypanosoma / Receptors, Cytoplasmic and Nuclear Type of study: Prognostic_studies Limits: Humans Language: En Journal: Sci Rep Year: 2022 Document type: Article Affiliation country: Poland Country of publication: United kingdom