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Genomic characterization of SARS-CoV-2 from vaccine breakthrough cases in Allegheny County, Pennsylvania.
Waggle, Kady D; Griffith, Marissa P; Zhu, Lei; Cooper, Vaughn S; Snyder, Daniel J; Srinivasa, Vatsala; Phan, Tung; Wells, Alan; Snyder, Graham M; Van Tyne, Daria; Harrison, Lee H; Marsh, Jane W.
Affiliation
  • Waggle KD; Microbial Genomics Epidemiology Laboratory, Center for Genomic Epidemiology, University of Pittsburgh, Pittsburgh, Pennsylvania, United States of America.
  • Griffith MP; Division of Infectious Diseases, University of Pittsburgh School of Medicine, Pittsburgh, Pennsylvania, United States of America.
  • Zhu L; Microbial Genomics Epidemiology Laboratory, Center for Genomic Epidemiology, University of Pittsburgh, Pittsburgh, Pennsylvania, United States of America.
  • Cooper VS; Division of Infectious Diseases, University of Pittsburgh School of Medicine, Pittsburgh, Pennsylvania, United States of America.
  • Snyder DJ; Microbial Genomics Epidemiology Laboratory, Center for Genomic Epidemiology, University of Pittsburgh, Pittsburgh, Pennsylvania, United States of America.
  • Srinivasa V; Division of Infectious Diseases, University of Pittsburgh School of Medicine, Pittsburgh, Pennsylvania, United States of America.
  • Phan T; Department of Microbiology and Molecular Genetics and Center for Evolutionary Biology and Medicine, University of Pittsburgh School of Medicine, Pittsburgh, Pennsylvania, United States of America.
  • Wells A; Microbial Genome Sequencing Center, LLC, Pittsburgh, Pennsylvania, United States of America.
  • Snyder GM; Microbial Genomics Epidemiology Laboratory, Center for Genomic Epidemiology, University of Pittsburgh, Pittsburgh, Pennsylvania, United States of America.
  • Van Tyne D; Division of Infectious Diseases, University of Pittsburgh School of Medicine, Pittsburgh, Pennsylvania, United States of America.
  • Harrison LH; Department of Pathology, University of Pittsburgh, Pittsburgh, Pennsylvania, United States of America.
  • Marsh JW; Department of Pathology, University of Pittsburgh, Pittsburgh, Pennsylvania, United States of America.
PLoS One ; 17(8): e0272954, 2022.
Article in En | MEDLINE | ID: mdl-36044529
ABSTRACT
We performed whole genome sequencing on SARS-CoV-2 from 59 vaccinated individuals from southwest Pennsylvania who tested positive between February and September, 2021. A comparison of mutations among vaccine breakthrough cases to a time-matched control group identified potential adaptive responses of SARS-CoV-2 to vaccination.
Subject(s)

Full text: 1 Collection: 01-internacional Database: MEDLINE Main subject: Viral Vaccines / COVID-19 Limits: Humans Country/Region as subject: America do norte Language: En Journal: PLoS One Journal subject: CIENCIA / MEDICINA Year: 2022 Document type: Article Affiliation country: United States

Full text: 1 Collection: 01-internacional Database: MEDLINE Main subject: Viral Vaccines / COVID-19 Limits: Humans Country/Region as subject: America do norte Language: En Journal: PLoS One Journal subject: CIENCIA / MEDICINA Year: 2022 Document type: Article Affiliation country: United States