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Quantum dots: The cutting-edge nanotheranostics in brain cancer management.
Chakraborty, Pratik; Das, Sabya Sachi; Dey, Abhijit; Chakraborty, Apala; Bhattacharyya, Chiranjib; Kandimalla, Ramesh; Mukherjee, Biswajit; Gopalakrishnan, Abilash Valsala; Singh, Sandeep Kumar; Kant, Shubham; Nand, Parma; Ojha, Shreesh; Kumar, Pravir; Jha, Niraj Kumar; Jha, Saurabh Kumar; Dewanjee, Saikat.
Affiliation
  • Chakraborty P; Advanced Pharmacognosy Research Laboratory, Department of Pharmaceutical Technology, Jadavpur University, Kolkata 700032, India.
  • Das SS; Department of Pharmaceutical Sciences and Technology, Birla Institute of Technology, Mesra, Ranchi, Jharkhand 835215, India; School of Pharmaceutical and Population Health Informatics, DIT University, Dehradun 248009, Uttarakhand, India.
  • Dey A; Pharmaceutics Research Laboratory, Department of Pharmaceutical Technology, Jadavpur University, Kolkata 700032, India.
  • Chakraborty A; Department of Life Sciences, Presidency University, Kolkata 700073, West Bengal, India.
  • Bhattacharyya C; Advanced Pharmacognosy Research Laboratory, Department of Pharmaceutical Technology, Jadavpur University, Kolkata 700032, India.
  • Kandimalla R; Department of Biochemistry, Kakatiya Medical College, Warangal 506007, Telangana, India; Applied Biology, CSIR-Indian Institute of Technology, Uppal Road, Hyderabad 500007, India.
  • Mukherjee B; Department of Life Sciences, Presidency University, Kolkata 700073, West Bengal, India.
  • Gopalakrishnan AV; Department of Biomedical Sciences, School of Bio Sciences and Technology, Vellore Institute of Technology (VIT), Vellore, Tamil Nadu 632014, India.
  • Singh SK; Department of Pharmaceutical Sciences and Technology, Birla Institute of Technology, Mesra, Ranchi, Jharkhand 835215, India.
  • Kant S; Department of Biotechnology, School of Engineering & Technology (SET), Sharda University, UP 201310, India.
  • Nand P; Department of Biotechnology, School of Engineering & Technology (SET), Sharda University, UP 201310, India.
  • Ojha S; Department of Pharmacology and Therapeutics, College of Medicine and Health Sciences, United Arab Emirates University, Al Ain, P.O. Box 15551, Abu Dhabi, United Arab Emirates.
  • Kumar P; Molecular Neuroscience and Functional Genomics Laboratory, Delhi Technological University (Formerly Delhi College of Engineering), Delhi, India.
  • Jha NK; Department of Biotechnology, School of Engineering & Technology (SET), Sharda University, UP 201310, India. Electronic address: nirajkumarjha2011@gmail.com.
  • Jha SK; Department of Biotechnology, School of Engineering & Technology (SET), Sharda University, UP 201310, India; Department of Biotechnology Engineering and Food Technology, Chandigarh University, Mohali 140413, India; Department of Biotechnology, School of Applied & Life Sciences (SALS), Uttaran
  • Dewanjee S; Advanced Pharmacognosy Research Laboratory, Department of Pharmaceutical Technology, Jadavpur University, Kolkata 700032, India. Electronic address: saikat.dewanjee@jadavpuruniversity.in.
J Control Release ; 350: 698-715, 2022 10.
Article in En | MEDLINE | ID: mdl-36057397
ABSTRACT
Quantum dots (QDs) are semiconductor nanocrystals possessing unique optoelectrical properties in that they can emit light energy of specific tunable wavelengths when excited by photons. They are gaining attention nowadays owing to their all-around ability to allow high-quality bio-imaging along with targeted drug delivery. The most lethal central nervous system (CNS) disorders are brain cancers or malignant brain tumors. CNS is guarded by the blood-brain barrier which poses a selective blockade toward drug delivery into the brain. QDs have displayed strong potential to deliver therapeutic agents into the brain successfully. Their bio-imaging capability due to photoluminescence and specific targeting ability through the attachment of ligand biomolecules make them preferable clinical tools for coming times. Biocompatible QDs are emerging as nanotheranostic tools to identify/diagnose and selectively kill cancer cells. The current review focuses on QDs and associated nanoformulations as potential futuristic clinical aids in the continuous battle against brain cancer.
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Full text: 1 Collection: 01-internacional Database: MEDLINE Main subject: Brain Neoplasms / Quantum Dots Limits: Humans Language: En Journal: J Control Release Journal subject: FARMACOLOGIA Year: 2022 Document type: Article Affiliation country: India
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Full text: 1 Collection: 01-internacional Database: MEDLINE Main subject: Brain Neoplasms / Quantum Dots Limits: Humans Language: En Journal: J Control Release Journal subject: FARMACOLOGIA Year: 2022 Document type: Article Affiliation country: India