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Discovery and preclinical evaluations of GST-HG131, a novel HBV antigen inhibitor for the treatment of chronic hepatitis B infection.
Hu, Yanbin; Sun, Fei; Yuan, Qiang; Du, Jinhua; Hu, Lihong; Gu, Zhengxian; Zhou, Qiong; Du, Xiaoting; He, Shibo; Sun, Ya; Wang, Qian; Fan, Lirong; Wang, Lina; Qin, Shaohua; Chen, Shuhui; Li, Jian; Wu, Wenqiang; Mao, John; Zhou, Yixin; Zhou, Qiaoyun; Zhang, George; Ding, Charles Z.
Affiliation
  • Hu Y; WuXi AppTec, 666 Gaoxin Road, East Lake High-tech Development Zone, Wuhan 430075, China.
  • Sun F; WuXi AppTec, 666 Gaoxin Road, East Lake High-tech Development Zone, Wuhan 430075, China.
  • Yuan Q; WuXi AppTec, 666 Gaoxin Road, East Lake High-tech Development Zone, Wuhan 430075, China.
  • Du J; WuXi AppTec, 666 Gaoxin Road, East Lake High-tech Development Zone, Wuhan 430075, China.
  • Hu L; WuXi AppTec, 666 Gaoxin Road, East Lake High-tech Development Zone, Wuhan 430075, China.
  • Gu Z; WuXi AppTec, 288 Fute Zhong Road, Waigaoqiao Free Trade Zone, Shanghai 200131, China.
  • Zhou Q; WuXi AppTec, 288 Fute Zhong Road, Waigaoqiao Free Trade Zone, Shanghai 200131, China.
  • Du X; WuXi AppTec, 288 Fute Zhong Road, Waigaoqiao Free Trade Zone, Shanghai 200131, China.
  • He S; WuXi AppTec, 288 Fute Zhong Road, Waigaoqiao Free Trade Zone, Shanghai 200131, China.
  • Sun Y; WuXi AppTec, 288 Fute Zhong Road, Waigaoqiao Free Trade Zone, Shanghai 200131, China.
  • Wang Q; WuXi AppTec, 288 Fute Zhong Road, Waigaoqiao Free Trade Zone, Shanghai 200131, China.
  • Fan L; WuXi AppTec, 288 Fute Zhong Road, Waigaoqiao Free Trade Zone, Shanghai 200131, China.
  • Wang L; WuXi AppTec, 288 Fute Zhong Road, Waigaoqiao Free Trade Zone, Shanghai 200131, China.
  • Qin S; WuXi AppTec, 288 Fute Zhong Road, Waigaoqiao Free Trade Zone, Shanghai 200131, China.
  • Chen S; WuXi AppTec, 288 Fute Zhong Road, Waigaoqiao Free Trade Zone, Shanghai 200131, China.
  • Li J; WuXi AppTec, 288 Fute Zhong Road, Waigaoqiao Free Trade Zone, Shanghai 200131, China.
  • Wu W; Fujian Akeylink Biotechnology Co.,Ltd, Fujian, China.
  • Mao J; Fujian Akeylink Biotechnology Co.,Ltd, Fujian, China.
  • Zhou Y; Fujian Akeylink Biotechnology Co.,Ltd, Fujian, China.
  • Zhou Q; Fujian Akeylink Biotechnology Co.,Ltd, Fujian, China.
  • Zhang G; Fujian Akeylink Biotechnology Co.,Ltd, Fujian, China.
  • Ding CZ; WuXi AppTec, 288 Fute Zhong Road, Waigaoqiao Free Trade Zone, Shanghai 200131, China. Electronic address: charles.ding@hotmail.com.
Bioorg Med Chem Lett ; 75: 128977, 2022 11 01.
Article in En | MEDLINE | ID: mdl-36089112
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Full text: 1 Collection: 01-internacional Database: MEDLINE Main subject: Hepatitis B, Chronic / Hepatitis B Limits: Animals Language: En Journal: Bioorg Med Chem Lett Journal subject: BIOQUIMICA / QUIMICA Year: 2022 Document type: Article Affiliation country: China Country of publication: United kingdom
Fulltext
Add to My VHL
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Full text: 1 Collection: 01-internacional Database: MEDLINE Main subject: Hepatitis B, Chronic / Hepatitis B Limits: Animals Language: En Journal: Bioorg Med Chem Lett Journal subject: BIOQUIMICA / QUIMICA Year: 2022 Document type: Article Affiliation country: China Country of publication: United kingdom