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A genetically modified minipig model for Alzheimer's disease with SORL1 haploinsufficiency.
Andersen, Olav M; Bøgh, Nikolaj; Landau, Anne M; Pløen, Gro G; Jensen, Anne Mette G; Monti, Giulia; Ulhøi, Benedicte P; Nyengaard, Jens R; Jacobsen, Kirsten R; Jørgensen, Margarita M; Holm, Ida E; Kristensen, Marianne L; Alstrup, Aage Kristian O; Hansen, Esben S S; Teunissen, Charlotte E; Breidenbach, Laura; Droescher, Mathias; Liu, Ying; Pedersen, Hanne S; Callesen, Henrik; Luo, Yonglun; Bolund, Lars; Brooks, David J; Laustsen, Christoffer; Small, Scott A; Mikkelsen, Lars F; Sørensen, Charlotte B.
Affiliation
  • Andersen OM; Department of Biomedicine, Aarhus University, Aarhus, Denmark. Electronic address: o.andersen@biomed.au.dk.
  • Bøgh N; Department of Clinical Medicine, Aarhus University, Aarhus, Denmark.
  • Landau AM; Department of Clinical Medicine, Aarhus University, Aarhus, Denmark.
  • Pløen GG; Department of Clinical Medicine, Aarhus University, Aarhus, Denmark.
  • Jensen AMG; Department of Biomedicine, Aarhus University, Aarhus, Denmark.
  • Monti G; Department of Biomedicine, Aarhus University, Aarhus, Denmark.
  • Ulhøi BP; Department of Pathology, Aarhus University Hospital, Aarhus, Denmark.
  • Nyengaard JR; Department of Clinical Medicine, Aarhus University, Aarhus, Denmark; Core Center for Molecular Morphology, Section for Stereology and Microscopy, Aarhus University, Aarhus, Denmark.
  • Jacobsen KR; Ellegaard Göttingen Minipigs A/S, Dalmose, Denmark.
  • Jørgensen MM; Department of Pathology, Randers Regional Hospital, Randers, Denmark.
  • Holm IE; Department of Pathology, Aalborg University Hospital, Aalborg, Denmark.
  • Kristensen ML; Department of Biomedicine, Aarhus University, Aarhus, Denmark.
  • Alstrup AKO; Department of Clinical Medicine, Aarhus University, Aarhus, Denmark; Department of Nuclear Medicine & PET-Centre, Aarhus University Hospital, Aarhus, Denmark.
  • Hansen ESS; Department of Clinical Medicine, Aarhus University, Aarhus, Denmark.
  • Teunissen CE; Department of Clinical Chemistry, Amsterdam University Medical Centers, Amsterdam, the Netherlands.
  • Breidenbach L; Neuroscience Research, AbbVie Deutschland GmbH & Co. KG, Ludwigshafen, Germany.
  • Droescher M; Neuroscience Research, AbbVie Deutschland GmbH & Co. KG, Ludwigshafen, Germany.
  • Liu Y; Department of Animal Science, Aarhus University, Tjele, Denmark.
  • Pedersen HS; Department of Animal Science, Aarhus University, Tjele, Denmark.
  • Callesen H; Department of Animal Science, Aarhus University, Tjele, Denmark.
  • Luo Y; Department of Biomedicine, Aarhus University, Aarhus, Denmark; Lars Bolund Institute of Regenerative Medicine, Qingdao-Europe Advanced Institute for Life Sciences, BGI-Shenzhen, Qingdao, China.
  • Bolund L; Department of Biomedicine, Aarhus University, Aarhus, Denmark; Lars Bolund Institute of Regenerative Medicine, Qingdao-Europe Advanced Institute for Life Sciences, BGI-Shenzhen, Qingdao, China.
  • Brooks DJ; Department of Clinical Medicine, Aarhus University, Aarhus, Denmark; Translational and Clinical Research Institute, University of Newcastle upon Tyne, Newcastle upon Tyne, UK.
  • Laustsen C; Department of Clinical Medicine, Aarhus University, Aarhus, Denmark.
  • Small SA; Department of Biomedicine, Aarhus University, Aarhus, Denmark; Department of Neurology and the Taub Institute for Research on Alzheimer's Disease and the Aging Brain, Columbia University, New York, NY, USA.
  • Mikkelsen LF; Ellegaard Göttingen Minipigs A/S, Dalmose, Denmark.
  • Sørensen CB; Department of Clinical Medicine, Aarhus University, Aarhus, Denmark. Electronic address: cbs@clin.au.dk.
Cell Rep Med ; 3(9): 100740, 2022 09 20.
Article in En | MEDLINE | ID: mdl-36099918

Full text: 1 Collection: 01-internacional Database: MEDLINE Main subject: Alzheimer Disease Limits: Animals / Humans Language: En Journal: Cell Rep Med Year: 2022 Document type: Article Country of publication: United States

Full text: 1 Collection: 01-internacional Database: MEDLINE Main subject: Alzheimer Disease Limits: Animals / Humans Language: En Journal: Cell Rep Med Year: 2022 Document type: Article Country of publication: United States