Determinants of late presentation of glaucoma in Hong Kong.
Eye (Lond)
; 37(8): 1717-1724, 2023 06.
Article
in En
| MEDLINE
| ID: mdl-36100709
ABSTRACT
BACKGROUND:
Glaucoma is the commonest cause of irreversible blindness worldwide. As it is typically asymptomatic until advanced, the risk of blindness from late presentation is higher than other eye diseases. This study aims to investigate the risk factors for late presentation of primary glaucoma patients.METHODS:
We undertook a hospital-based case-control study of a random sample of glaucoma patients from a hospital in Hong Kong. Structured questionnaires and existing information from the electronic patient record were used, and the odds of presenting late were analysed by logistic regression.RESULTS:
Of 210 recruited participants, 83 (39.5%) presented with advanced glaucoma unilaterally or bilaterally. The mean age of participants was 61.1 ± 11.9 years, with 110 males (52.4%). Univariate analysis revealed that male sex and primary angle-closure glaucoma (PACG) have 3.06 (CI951.71-5.48; P < 0.001) and 2.47 (CI951.11-5.49; P = 0.03) times higher odds of late presentation, respectively. Multivariate analysis revealed late presenters were 3.54 (CI951.35-9.35; P = 0.01) times more likely to have PACG than primary open-angle glaucoma (POAG). Patients with elevated baseline intraocular pressure (IOP) also had 1.06 times higher odds of presenting with advanced glaucoma (CI951.02-1.11; P = 0.002). Linear regression revealed that PACG patients present with 7.12 mmHg higher IOP than POAG patients (CI954.23-10.0; P < 0.001).CONCLUSION:
In conclusion, a high proportion of glaucoma patients present late in Hong Kong, with gender and type of glaucoma being significant determinants. Our study shows that PACG presents with higher IOP and, along with male gender, are more likely to have advanced disease than POAG.
Full text:
1
Collection:
01-internacional
Database:
MEDLINE
Main subject:
Glaucoma, Angle-Closure
/
Glaucoma, Open-Angle
Type of study:
Observational_studies
/
Qualitative_research
/
Risk_factors_studies
Limits:
Aged
/
Humans
/
Male
/
Middle aged
Country/Region as subject:
Asia
Language:
En
Journal:
Eye (Lond)
Journal subject:
OFTALMOLOGIA
Year:
2023
Document type:
Article
Affiliation country:
United kingdom