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Keep calm and transcribe on: chromatin changes with age, but transcription can learn to live with it.
Lynch, Cian J; Serrano, Manuel.
Affiliation
  • Lynch CJ; Cellular Plasticity and Disease Group, Institute for Research in Biomedicine (IRB Barcelona), Barcelona Institute of Science and Technology (BIST), Barcelona, Spain.
  • Serrano M; Cellular Plasticity and Disease Group, Institute for Research in Biomedicine (IRB Barcelona), Barcelona Institute of Science and Technology (BIST), Barcelona, Spain.
Mol Syst Biol ; 18(9): e11276, 2022 09.
Article in En | MEDLINE | ID: mdl-36102256
ABSTRACT
Assessing age-related tissue dysfunction represents an emerging field and involves analyses that are far from trivial, often requiring the integration of several large-scale ("omic") techniques. In their recent work, Tessarz and colleagues (Bozukova et al, 2022) characterize changes in the transcriptional machinery during aging in mice and report some surprising findings.
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Full text: 1 Collection: 01-internacional Database: MEDLINE Main subject: Transcription, Genetic / Chromatin Limits: Animals Language: En Journal: Mol Syst Biol Journal subject: BIOLOGIA MOLECULAR / BIOTECNOLOGIA Year: 2022 Document type: Article Affiliation country: Spain
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Full text: 1 Collection: 01-internacional Database: MEDLINE Main subject: Transcription, Genetic / Chromatin Limits: Animals Language: En Journal: Mol Syst Biol Journal subject: BIOLOGIA MOLECULAR / BIOTECNOLOGIA Year: 2022 Document type: Article Affiliation country: Spain