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Adjunctive therapy with the Tie2 agonist Vasculotide reduces pulmonary permeability in Streptococcus pneumoniae infected and mechanically ventilated mice.
Lask, Aina; Gutbier, Birgitt; Kershaw, Olivia; Nouailles, Geraldine; Gruber, Achim D; Müller-Redetzky, Holger C; Chackowicz, Steven; Hamilton, Douglas A; Van Slyke, Paul; Witzenrath, Martin.
Affiliation
  • Lask A; Department of Infectious Diseases and Respiratory Medicine, Charité-Universitätsmedizin Berlin, corporate member of Freie Universität Berlin and Humboldt-Universität zu Berlin, Charitéplatz 1, 10117, Berlin, Germany.
  • Gutbier B; Department of Infectious Diseases and Respiratory Medicine, Charité-Universitätsmedizin Berlin, corporate member of Freie Universität Berlin and Humboldt-Universität zu Berlin, Charitéplatz 1, 10117, Berlin, Germany. birgitt.gutbier@charite.de.
  • Kershaw O; Department of Veterinary Pathology, Freie Universität Berlin, Berlin, Germany.
  • Nouailles G; Department of Infectious Diseases and Respiratory Medicine, Charité-Universitätsmedizin Berlin, corporate member of Freie Universität Berlin and Humboldt-Universität zu Berlin, Charitéplatz 1, 10117, Berlin, Germany.
  • Gruber AD; Department of Veterinary Pathology, Freie Universität Berlin, Berlin, Germany.
  • Müller-Redetzky HC; Department of Infectious Diseases and Respiratory Medicine, Charité-Universitätsmedizin Berlin, corporate member of Freie Universität Berlin and Humboldt-Universität zu Berlin, Charitéplatz 1, 10117, Berlin, Germany.
  • Chackowicz S; Vasomune Therapeutics, Sunnybrook Research Institute, S-Wing Rm 227, 2075 Bayview Avenue, Toronto, ON, M4N3M5, Canada.
  • Hamilton DA; Vasomune Therapeutics, Sunnybrook Research Institute, S-Wing Rm 227, 2075 Bayview Avenue, Toronto, ON, M4N3M5, Canada.
  • Van Slyke P; Vasomune Therapeutics, Sunnybrook Research Institute, S-Wing Rm 227, 2075 Bayview Avenue, Toronto, ON, M4N3M5, Canada.
  • Witzenrath M; Department of Infectious Diseases and Respiratory Medicine, Charité-Universitätsmedizin Berlin, corporate member of Freie Universität Berlin and Humboldt-Universität zu Berlin, Charitéplatz 1, 10117, Berlin, Germany. martin.witzenrath@charite.de.
Sci Rep ; 12(1): 15531, 2022 09 15.
Article in En | MEDLINE | ID: mdl-36109537
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Full text: 1 Collection: 01-internacional Database: MEDLINE Main subject: Pneumonia, Pneumococcal / Receptor, TIE-2 / Ventilator-Induced Lung Injury Limits: Animals Language: En Journal: Sci Rep Year: 2022 Document type: Article Affiliation country: Germany Country of publication: United kingdom
Fulltext
Add to My VHL
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Full text: 1 Collection: 01-internacional Database: MEDLINE Main subject: Pneumonia, Pneumococcal / Receptor, TIE-2 / Ventilator-Induced Lung Injury Limits: Animals Language: En Journal: Sci Rep Year: 2022 Document type: Article Affiliation country: Germany Country of publication: United kingdom