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Metabolic targeting of NRF2 potentiates the efficacy of the TRAP1 inhibitor G-TPP through reduction of ROS detoxification in colorectal cancer.
Tsai, Hong-Yuan; Bronner, Mary P; March, Jordon K; Valentine, John F; Shroyer, Noah F; Lai, Lisa A; Brentnall, Teresa A; Pan, Sheng; Chen, Ru.
Affiliation
  • Tsai HY; Section of Gastroenterology and Hepatology, Department of Medicine, Baylor College of Medicine, Houston, TX, USA. Electronic address: Hong-Yuan.Tsai@bcm.edu.
  • Bronner MP; Department of Pathology, University of Utah, Salt Lake City, UT, USA; Huntsman Cancer Institute, University of Utah, Salt Lake City, UT, USA.
  • March JK; Department of Pathology, University of Utah, Salt Lake City, UT, USA.
  • Valentine JF; Division of Gastroenterology, Hepatology and Nutrition, Department of Internal Medicine, University of Utah, Salt Lake City, UT, USA.
  • Shroyer NF; Section of Gastroenterology and Hepatology, Department of Medicine, Baylor College of Medicine, Houston, TX, USA.
  • Lai LA; Department of Medicine, University of Washington, Seattle, WA, USA.
  • Brentnall TA; Department of Medicine, University of Washington, Seattle, WA, USA.
  • Pan S; Brown Foundation Institute of Molecular Medicine, McGovern Medical School, University of Texas Health Science Center at Houston, Houston, TX, USA.
  • Chen R; Section of Gastroenterology and Hepatology, Department of Medicine, Baylor College of Medicine, Houston, TX, USA. Electronic address: ru.chen@bcm.edu.
Cancer Lett ; 549: 215915, 2022 11 28.
Article in En | MEDLINE | ID: mdl-36113636
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Full text: 1 Collection: 01-internacional Database: MEDLINE Main subject: Colorectal Neoplasms / Colonic Neoplasms Limits: Humans Language: En Journal: Cancer Lett Year: 2022 Document type: Article Country of publication: Ireland
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Full text: 1 Collection: 01-internacional Database: MEDLINE Main subject: Colorectal Neoplasms / Colonic Neoplasms Limits: Humans Language: En Journal: Cancer Lett Year: 2022 Document type: Article Country of publication: Ireland