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First-in-Class Small Molecule to Inhibit CYP11A1 and Steroid Hormone Biosynthesis.
Karimaa, Mari; Riikonen, Reetta; Kettunen, Henna; Taavitsainen, Päivi; Ramela, Meri; Chrusciel, Marcin; Karlsson, Stefan; Rummakko, Petteri; Simola, Outi; Wohlfahrt, Gerd; Hakulinen, Pasi; Vuorela, Annamari; Joensuu, Heikki; Utriainen, Tapio; Fizazi, Karim; Oksala, Riikka.
Affiliation
  • Karimaa M; Orion Corporation Orion Pharma, Espoo, Finland.
  • Riikonen R; Orion Corporation Orion Pharma, Espoo, Finland.
  • Kettunen H; Orion Corporation Orion Pharma, Espoo, Finland.
  • Taavitsainen P; Orion Corporation Orion Pharma, Espoo, Finland.
  • Ramela M; Orion Corporation Orion Pharma, Espoo, Finland.
  • Chrusciel M; Orion Corporation Orion Pharma, Espoo, Finland.
  • Karlsson S; Orion Corporation Orion Pharma, Espoo, Finland.
  • Rummakko P; Orion Corporation Orion Pharma, Espoo, Finland.
  • Simola O; Orion Corporation Orion Pharma, Espoo, Finland.
  • Wohlfahrt G; Orion Corporation Orion Pharma, Espoo, Finland.
  • Hakulinen P; Orion Corporation Orion Pharma, Espoo, Finland.
  • Vuorela A; Orion Corporation Orion Pharma, Espoo, Finland.
  • Joensuu H; Helsinki University Hospital and University of Helsinki, Helsinki, Finland.
  • Utriainen T; Helsinki University Hospital and University of Helsinki, Helsinki, Finland.
  • Fizazi K; Department of Cancer Medicine, Institut Gustave Roussy, University of Paris Saclay, Villejuif, France.
  • Oksala R; Orion Corporation Orion Pharma, Espoo, Finland.
Mol Cancer Ther ; 21(12): 1765-1776, 2022 12 02.
Article in En | MEDLINE | ID: mdl-36129801
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Full text: 1 Collection: 01-internacional Database: MEDLINE Main subject: Adrenal Cortex Neoplasms / Prostatic Neoplasms, Castration-Resistant Type of study: Prognostic_studies Limits: Animals / Humans / Male Language: En Journal: Mol Cancer Ther Journal subject: ANTINEOPLASICOS Year: 2022 Document type: Article Affiliation country: Finland Country of publication: United States
Fulltext
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Full text: 1 Collection: 01-internacional Database: MEDLINE Main subject: Adrenal Cortex Neoplasms / Prostatic Neoplasms, Castration-Resistant Type of study: Prognostic_studies Limits: Animals / Humans / Male Language: En Journal: Mol Cancer Ther Journal subject: ANTINEOPLASICOS Year: 2022 Document type: Article Affiliation country: Finland Country of publication: United States