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Design, synthesis, and biological evaluation of low-toxic lappaconitine derivatives as potential analgesics.
Li, Yuzhu; Shang, Yushan; Li, Xiaohuan; Zhang, Yinyong; Xie, Jiang; Chen, Lin; Gao, Feng; Zhou, Xian-Li.
Affiliation
  • Li Y; Sichuan Engineering Research Center for Biomimetic Synthesis of Natural Drugs, School of Life Science and Engineering, Southwest Jiaotong University, Chengdu, 610031, PR China.
  • Shang Y; Sichuan Engineering Research Center for Biomimetic Synthesis of Natural Drugs, School of Life Science and Engineering, Southwest Jiaotong University, Chengdu, 610031, PR China.
  • Li X; Sichuan Engineering Research Center for Biomimetic Synthesis of Natural Drugs, School of Life Science and Engineering, Southwest Jiaotong University, Chengdu, 610031, PR China.
  • Zhang Y; Sichuan Engineering Research Center for Biomimetic Synthesis of Natural Drugs, School of Life Science and Engineering, Southwest Jiaotong University, Chengdu, 610031, PR China.
  • Xie J; Southwest Jiaotong University, Affiliated Hospital, The Third People's Hospital of Chengdu, Chengdu, 610000, PR China.
  • Chen L; Sichuan Engineering Research Center for Biomimetic Synthesis of Natural Drugs, School of Life Science and Engineering, Southwest Jiaotong University, Chengdu, 610031, PR China. Electronic address: linch@swjtu.edu.cn.
  • Gao F; Sichuan Engineering Research Center for Biomimetic Synthesis of Natural Drugs, School of Life Science and Engineering, Southwest Jiaotong University, Chengdu, 610031, PR China. Electronic address: gaof@swjtu.edu.cn.
  • Zhou XL; Sichuan Engineering Research Center for Biomimetic Synthesis of Natural Drugs, School of Life Science and Engineering, Southwest Jiaotong University, Chengdu, 610031, PR China; Southwest Jiaotong University, Affiliated Hospital, The Third People's Hospital of Chengdu, Chengdu, 610000, PR China. Elec
Eur J Med Chem ; 243: 114776, 2022 Dec 05.
Article in En | MEDLINE | ID: mdl-36162215
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Full text: 1 Collection: 01-internacional Database: MEDLINE Main subject: Aconitine / Tandem Mass Spectrometry Language: En Journal: Eur J Med Chem Year: 2022 Document type: Article Country of publication: France
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Full text: 1 Collection: 01-internacional Database: MEDLINE Main subject: Aconitine / Tandem Mass Spectrometry Language: En Journal: Eur J Med Chem Year: 2022 Document type: Article Country of publication: France