CEPsh glia development is not required for general AWC identity or AWC asymmetry.
MicroPubl Biol
; 20222022.
Article
in En
| MEDLINE
| ID: mdl-36188097
ABSTRACT
The Caenorhabditis elegans VAB-3/Pax6 homeodomain protein was previously shown to play a role in both the development of cephalic sheath (CEPsh) glia and asymmetric differentiation of AWC olfactory neuron subtypes AWC ON /AWC OFF . Here we show that vab-3 is not required for the specification of general AWC identity. We also show that some vab-3 mutant alleles with defective CEPsh glia development displayed wild-type AWC asymmetry. These results suggest that vab-3 has separable roles in CEPsh glia development and AWC asymmetry. Together, our results suggest that general AWC identity and AWC asymmetry are not dependent on the development of CEPsh glia.
Full text:
1
Collection:
01-internacional
Database:
MEDLINE
Language:
En
Journal:
MicroPubl Biol
Year:
2022
Document type:
Article
Affiliation country:
United States