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Volanesorsen, an antisense oligonucleotide to apolipoprotein C-III, increases lipoprotein lipase activity and lowers triglycerides in partial lipodystrophy.
Lightbourne, Marissa; Startzell, Megan; Bruce, Kimberley D; Brite, Brianna; Muniyappa, Ranganath; Skarulis, Monica; Shamburek, Robert; Gharib, Ahmed M; Ouwerkerk, Ronald; Walter, Mary; Eckel, Robert H; Brown, Rebecca J.
Affiliation
  • Lightbourne M; National Institute of Diabetes and Digestive and Kidney Diseases, National Institutes of Health, Bethesda, MD, USA.
  • Startzell M; National Institute of Diabetes and Digestive and Kidney Diseases, National Institutes of Health, Bethesda, MD, USA.
  • Bruce KD; Division of Endocrinology, Metabolism and Diabetes, School of Medicine, University of Colorado Anschutz Medical Campus, Aurora, CO, USA.
  • Brite B; National Institute of Diabetes and Digestive and Kidney Diseases, National Institutes of Health, Bethesda, MD, USA.
  • Muniyappa R; National Institute of Diabetes and Digestive and Kidney Diseases, National Institutes of Health, Bethesda, MD, USA.
  • Skarulis M; National Institute of Diabetes and Digestive and Kidney Diseases, National Institutes of Health, Bethesda, MD, USA.
  • Shamburek R; Cardiovascular Branch, National Heart, Lung, and Blood Institute, National Institutes of Health, Bethesda, MD, USA.
  • Gharib AM; National Institute of Diabetes and Digestive and Kidney Diseases, National Institutes of Health, Bethesda, MD, USA.
  • Ouwerkerk R; National Institute of Diabetes and Digestive and Kidney Diseases, National Institutes of Health, Bethesda, MD, USA.
  • Walter M; National Institute of Diabetes and Digestive and Kidney Diseases, National Institutes of Health, Bethesda, MD, USA.
  • Eckel RH; Division of Endocrinology, Metabolism and Diabetes, School of Medicine, University of Colorado Anschutz Medical Campus, Aurora, CO, USA.
  • Brown RJ; National Institute of Diabetes and Digestive and Kidney Diseases, National Institutes of Health, Bethesda, MD, USA. Electronic address: brownrebecca@mail.nih.gov.
J Clin Lipidol ; 16(6): 850-862, 2022.
Article in En | MEDLINE | ID: mdl-36195542
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Full text: 1 Collection: 01-internacional Database: MEDLINE Main subject: Insulin Resistance / Hypertriglyceridemia / Lipodystrophy Type of study: Clinical_trials Limits: Adult / Humans Language: En Journal: J Clin Lipidol Journal subject: BIOQUIMICA / METABOLISMO Year: 2022 Document type: Article Affiliation country: United States Country of publication: United States
Fulltext
Add to My VHL
Print
XML
PubMed Links
Search on Google

Full text: 1 Collection: 01-internacional Database: MEDLINE Main subject: Insulin Resistance / Hypertriglyceridemia / Lipodystrophy Type of study: Clinical_trials Limits: Adult / Humans Language: En Journal: J Clin Lipidol Journal subject: BIOQUIMICA / METABOLISMO Year: 2022 Document type: Article Affiliation country: United States Country of publication: United States