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PRL2 phosphatase enhances oncogenic FLT3 signaling via dephosphorylation of the E3 ubiquitin ligase CBL at tyrosine 371.
Chen, Hongxia; Bai, Yunpeng; Kobayashi, Michihiro; Xiao, Shiyu; Cai, Wenjie; Barajas, Sergio; Chen, Sisi; Miao, Jinmin; Meke, Frederick Nguele; Vemula, Sasidhar; Ropa, James P; Croop, James M; Boswell, H Scott; Wan, Jun; Jia, Yuzhi; Liu, Huiping; Li, Loretta S; Altman, Jessica K; Eklund, Elizabeth A; Ji, Peng; Tong, Wei; Band, Hamid; Huang, Danny T; Platanias, Leonidas C; Zhang, Zhong-Yin; Liu, Yan.
Affiliation
  • Chen H; Department of Hematology and Oncology, Chongqing University Three Gorges Hospital, Chongqing, China.
  • Bai Y; Department of Medicine, Feinberg School of Medicine, Northwestern University, Chicago, IL.
  • Kobayashi M; School of Medicine, Chongqing University, Chongqing, China.
  • Xiao S; Department of Medicinal Chemistry and Molecular Pharmacology, Center for Cancer Research, and Institute for Drug Discovery, Purdue University, West Lafayette, IN.
  • Cai W; Department of Pediatrics, Herman B Wells Center for Pediatric Research, Indiana University School of Medicine, Indianapolis, IN.
  • Barajas S; Department of Medicine, Feinberg School of Medicine, Northwestern University, Chicago, IL.
  • Chen S; Department of Medicine, Feinberg School of Medicine, Northwestern University, Chicago, IL.
  • Miao J; Department of Pediatrics, Herman B Wells Center for Pediatric Research, Indiana University School of Medicine, Indianapolis, IN.
  • Meke FN; Department of Medicine, Feinberg School of Medicine, Northwestern University, Chicago, IL.
  • Vemula S; Department of Pediatrics, Herman B Wells Center for Pediatric Research, Indiana University School of Medicine, Indianapolis, IN.
  • Ropa JP; Department of Pediatrics, Herman B Wells Center for Pediatric Research, Indiana University School of Medicine, Indianapolis, IN.
  • Croop JM; Department of Medicinal Chemistry and Molecular Pharmacology, Center for Cancer Research, and Institute for Drug Discovery, Purdue University, West Lafayette, IN.
  • Boswell HS; Department of Medicinal Chemistry and Molecular Pharmacology, Center for Cancer Research, and Institute for Drug Discovery, Purdue University, West Lafayette, IN.
  • Wan J; Department of Pediatrics, Herman B Wells Center for Pediatric Research, Indiana University School of Medicine, Indianapolis, IN.
  • Jia Y; Department of Microbiology and Immunology, Indiana University School of Medicine, Indianapolis, IN.
  • Liu H; Department of Pediatrics, Herman B Wells Center for Pediatric Research, Indiana University School of Medicine, Indianapolis, IN.
  • Li LS; Department of Medicine, Indiana University School of Medicine, Indianapolis, IN.
  • Altman JK; Department of Medical Genetics, Indiana University, Indianapolis, IN.
  • Eklund EA; Department of Pharmacology, Feinberg School of Medicine, Northwestern University, Chicago, IL.
  • Ji P; Department of Pharmacology, Feinberg School of Medicine, Northwestern University, Chicago, IL.
  • Tong W; Robert H. Lurie Comprehensive Cancer Center, Chicago, IL.
  • Band H; Robert H. Lurie Comprehensive Cancer Center, Chicago, IL.
  • Huang DT; Department of Pediatrics, Feinberg School of Medicine, Northwestern University, Chicago, IL.
  • Platanias LC; Department of Medicine, Feinberg School of Medicine, Northwestern University, Chicago, IL.
  • Zhang ZY; Robert H. Lurie Comprehensive Cancer Center, Chicago, IL.
  • Liu Y; Department of Medicine, Feinberg School of Medicine, Northwestern University, Chicago, IL.
Blood ; 141(3): 244-259, 2023 01 19.
Article in En | MEDLINE | ID: mdl-36206490
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Full text: 1 Collection: 01-internacional Database: MEDLINE Main subject: Leukemia, Myeloid, Acute / Ubiquitin-Protein Ligases Limits: Animals / Humans Language: En Journal: Blood Year: 2023 Document type: Article Affiliation country: China
Fulltext
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Full text: 1 Collection: 01-internacional Database: MEDLINE Main subject: Leukemia, Myeloid, Acute / Ubiquitin-Protein Ligases Limits: Animals / Humans Language: En Journal: Blood Year: 2023 Document type: Article Affiliation country: China