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A multi-omic analysis of MCF10A cells provides a resource for integrative assessment of ligand-mediated molecular and phenotypic responses.
Gross, Sean M; Dane, Mark A; Smith, Rebecca L; Devlin, Kaylyn L; McLean, Ian C; Derrick, Daniel S; Mills, Caitlin E; Subramanian, Kartik; London, Alexandra B; Torre, Denis; Evangelista, John Erol; Clarke, Daniel J B; Xie, Zhuorui; Erdem, Cemal; Lyons, Nicholas; Natoli, Ted; Pessa, Sarah; Lu, Xiaodong; Mullahoo, James; Li, Jonathan; Adam, Miriam; Wassie, Brook; Liu, Moqing; Kilburn, David F; Liby, Tiera A; Bucher, Elmar; Sanchez-Aguila, Crystal; Daily, Kenneth; Omberg, Larsson; Wang, Yunguan; Jacobson, Connor; Yapp, Clarence; Chung, Mirra; Vidovic, Dusica; Lu, Yiling; Schurer, Stephan; Lee, Albert; Pillai, Ajay; Subramanian, Aravind; Papanastasiou, Malvina; Fraenkel, Ernest; Feiler, Heidi S; Mills, Gordon B; Jaffe, Jake D; Ma'ayan, Avi; Birtwistle, Marc R; Sorger, Peter K; Korkola, James E; Gray, Joe W; Heiser, Laura M.
Affiliation
  • Gross SM; Department of Biomedical Engineering, OHSU, Portland, OR, USA.
  • Dane MA; Department of Biomedical Engineering, OHSU, Portland, OR, USA.
  • Smith RL; Department of Biomedical Engineering, OHSU, Portland, OR, USA.
  • Devlin KL; Department of Biomedical Engineering, OHSU, Portland, OR, USA.
  • McLean IC; Department of Biomedical Engineering, OHSU, Portland, OR, USA.
  • Derrick DS; Department of Biomedical Engineering, OHSU, Portland, OR, USA.
  • Mills CE; Laboratory of Systems Pharmacology, Department of Systems Biology, Harvard Program in Therapeutic Science, Harvard Medical School, Boston, MA, USA.
  • Subramanian K; Laboratory of Systems Pharmacology, Department of Systems Biology, Harvard Program in Therapeutic Science, Harvard Medical School, Boston, MA, USA.
  • London AB; Department of Pharmacological Sciences, Mount Sinai Center for Bioinformatics, Icahn School of Medicine at Mount Sinai, New York, NY, USA.
  • Torre D; Department of Pharmacological Sciences, Mount Sinai Center for Bioinformatics, Icahn School of Medicine at Mount Sinai, New York, NY, USA.
  • Evangelista JE; Department of Pharmacological Sciences, Mount Sinai Center for Bioinformatics, Icahn School of Medicine at Mount Sinai, New York, NY, USA.
  • Clarke DJB; Department of Pharmacological Sciences, Mount Sinai Center for Bioinformatics, Icahn School of Medicine at Mount Sinai, New York, NY, USA.
  • Xie Z; Department of Pharmacological Sciences, Mount Sinai Center for Bioinformatics, Icahn School of Medicine at Mount Sinai, New York, NY, USA.
  • Erdem C; Department of Chemical and Biomolecular Engineering, Clemson University, Clemson, SC, USA.
  • Lyons N; Broad Institute of MIT and Harvard, Cambridge, MA, USA.
  • Natoli T; Broad Institute of MIT and Harvard, Cambridge, MA, USA.
  • Pessa S; Broad Institute of MIT and Harvard, Cambridge, MA, USA.
  • Lu X; Broad Institute of MIT and Harvard, Cambridge, MA, USA.
  • Mullahoo J; Broad Institute of MIT and Harvard, Cambridge, MA, USA.
  • Li J; Department of Biological Engineering, Massachusetts Institute of Technology, Cambridge, MA, USA.
  • Adam M; Department of Biological Engineering, Massachusetts Institute of Technology, Cambridge, MA, USA.
  • Wassie B; Department of Biological Engineering, Massachusetts Institute of Technology, Cambridge, MA, USA.
  • Liu M; Department of Biomedical Engineering, OHSU, Portland, OR, USA.
  • Kilburn DF; Department of Biomedical Engineering, OHSU, Portland, OR, USA.
  • Liby TA; Department of Biomedical Engineering, OHSU, Portland, OR, USA.
  • Bucher E; Department of Biomedical Engineering, OHSU, Portland, OR, USA.
  • Sanchez-Aguila C; Department of Biomedical Engineering, OHSU, Portland, OR, USA.
  • Daily K; Sage Bionetworks, Seattle, WA, USA.
  • Omberg L; Sage Bionetworks, Seattle, WA, USA.
  • Wang Y; Laboratory of Systems Pharmacology, Department of Systems Biology, Harvard Program in Therapeutic Science, Harvard Medical School, Boston, MA, USA.
  • Jacobson C; Laboratory of Systems Pharmacology, Department of Systems Biology, Harvard Program in Therapeutic Science, Harvard Medical School, Boston, MA, USA.
  • Yapp C; Laboratory of Systems Pharmacology, Department of Systems Biology, Harvard Program in Therapeutic Science, Harvard Medical School, Boston, MA, USA.
  • Chung M; Laboratory of Systems Pharmacology, Department of Systems Biology, Harvard Program in Therapeutic Science, Harvard Medical School, Boston, MA, USA.
  • Vidovic D; Sylvester Comprehensive Cancer Center, University of Miami, Miami, FL, 33136, USA.
  • Lu Y; Department of Molecular and Cellular Pharmacology, Miller School of Medicine, University of Miami, Miami, FL, 33136, USA.
  • Schurer S; Institute for Data Science & Computing, University of Miami, Miami, FL, 33136, USA.
  • Lee A; Department of Genomic Medicine, Division of Cancer Medicine, The University of Texas MD Anderson Cancer Center, Houston, TX, USA.
  • Pillai A; Sylvester Comprehensive Cancer Center, University of Miami, Miami, FL, 33136, USA.
  • Subramanian A; Department of Molecular and Cellular Pharmacology, Miller School of Medicine, University of Miami, Miami, FL, 33136, USA.
  • Papanastasiou M; Institute for Data Science & Computing, University of Miami, Miami, FL, 33136, USA.
  • Fraenkel E; Heart, Lung, and Blood Institute, National Institutes of Health, Bethesda, USA.
  • Feiler HS; Human Genome Research Institute, National Institutes of Health, Bethesda, USA.
  • Mills GB; Broad Institute of MIT and Harvard, Cambridge, MA, USA.
  • Jaffe JD; Broad Institute of MIT and Harvard, Cambridge, MA, USA.
  • Ma'ayan A; Broad Institute of MIT and Harvard, Cambridge, MA, USA.
  • Birtwistle MR; Department of Biological Engineering, Massachusetts Institute of Technology, Cambridge, MA, USA.
  • Sorger PK; Department of Biomedical Engineering, OHSU, Portland, OR, USA.
  • Korkola JE; Knight Cancer Institute, OHSU, Portland, OR, USA.
  • Gray JW; Knight Cancer Institute, OHSU, Portland, OR, USA.
  • Heiser LM; Division of Oncological Sciences, OHSU, Portland, OR, USA.
Commun Biol ; 5(1): 1066, 2022 10 07.
Article in En | MEDLINE | ID: mdl-36207580
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Full text: 1 Collection: 01-internacional Database: MEDLINE Main subject: Proteomics / Epidermal Growth Factor Language: En Journal: Commun Biol Year: 2022 Document type: Article Affiliation country: United States Country of publication: United kingdom
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Full text: 1 Collection: 01-internacional Database: MEDLINE Main subject: Proteomics / Epidermal Growth Factor Language: En Journal: Commun Biol Year: 2022 Document type: Article Affiliation country: United States Country of publication: United kingdom