The Impact of Supportive Housing on Liver-Related Outcomes Among Persons With Hepatitis C Virus Infection.
J Infect Dis
; 226(Suppl 3): S363-S371, 2022 10 07.
Article
in En
| MEDLINE
| ID: mdl-36208165
ABSTRACT
BACKGROUND:
Hepatitis C virus (HCV) infection disproportionately impacts people experiencing homelessness. Hepatitis C virus can lead to negative health outcomes, including mortality. We evaluated the impact of a permanent supportive housing (PSH) program (ie, "treatment") on liver-related morbidity and mortality among persons with chronic homelessness and HCV infection.METHODS:
We matched records for persons eligible for a New York City PSH program (2007-2014) with Heath Department HCV and Vital Statistics registries and Medicaid claims. Among persons diagnosed with HCV before or 2 years posteligibility, we added stabilized inverse probability of treatment weights to negative binomial regression models to compare rates for liver disease-related emergency department visits and hospitalizations, and hazard ratios for mortality, by program placement 2 and 5 years posteligibility.RESULTS:
We identified 1158 of 8783 placed and 1952 of 19 019 unplaced persons with laboratory-confirmed HCV infection. Permanent supportive housing placement was associated with significantly reduced liver-related emergency department visits (adjusted rate ratio [aRR] = 0.76, 95% confidence interval [CI] = .61-.95), hospitalizations (aRR = 0.62, 95% CI = .54-.71), and all-cause (adjusted hazard ratio [aHR] = 0.65, 95% CI = .46-.92) and liver-related mortality (aHR = 0.72, 95% CI = .09-.83) within 2 years. The reduction remained significant for hospitalizations after 5 years.CONCLUSIONS:
Placement into PSH was associated with reduced liver-related morbidity and mortality among persons with HCV infection and chronic homelessness.Key words
Full text:
1
Collection:
01-internacional
Database:
MEDLINE
Main subject:
Ill-Housed Persons
/
Hepatitis C
Limits:
Humans
Language:
En
Journal:
J Infect Dis
Year:
2022
Document type:
Article
Affiliation country:
United States