Cyclosporine-induced gingival overgrowth-Review.
Dermatol Ther
; 35(12): e15912, 2022 12.
Article
in En
| MEDLINE
| ID: mdl-36208445
ABSTRACT
Drug-induced gingival overgrowth (DIGO) is an undesirable effect resulting from the therapy of one of the three groups of drugs phenytoin, calcium channel blockers, and cyclosporine A (CsA). It is caused by a fibrous overgrowth leading to gingivitis, periodontitis, and even tooth loss. Possible consequences include tooth decay worsening, pain and difficulty in eating, bleeding gums, and bad breath. The pathomechanism of the hypertrophy is unknown, but there is a correlation between insufficient oral hygiene and the severity of this phenomenon. The gender and age predilection of gingival hyperplasia as a result of CsA therapy is also noticeable. It is most common in children and adolescents of the male sex. The beneficial effect of the removal of tartar and local irritants in reducing the above symptoms has been demonstrated. One of the treatments for DIGO is conventional gingivectomy. The paper is a review article about cyclosporine-induced gingival hyperplasia.
Key words
Full text:
1
Collection:
01-internacional
Database:
MEDLINE
Main subject:
Gingival Overgrowth
/
Gingival Hyperplasia
Limits:
Adolescent
/
Child
/
Humans
/
Male
Language:
En
Journal:
Dermatol Ther
Journal subject:
DERMATOLOGIA
Year:
2022
Document type:
Article
Affiliation country:
Poland