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A comprehensive SARS-CoV-2-human protein-protein interactome reveals COVID-19 pathobiology and potential host therapeutic targets.
Zhou, Yadi; Liu, Yuan; Gupta, Shagun; Paramo, Mauricio I; Hou, Yuan; Mao, Chengsheng; Luo, Yuan; Judd, Julius; Wierbowski, Shayne; Bertolotti, Marta; Nerkar, Mriganka; Jehi, Lara; Drayman, Nir; Nicolaescu, Vlad; Gula, Haley; Tay, Savas; Randall, Glenn; Wang, Peihui; Lis, John T; Feschotte, Cédric; Erzurum, Serpil C; Cheng, Feixiong; Yu, Haiyuan.
Affiliation
  • Zhou Y; Genomic Medicine Institute, Lerner Research Institute, Cleveland Clinic, Cleveland, OH, USA.
  • Liu Y; Weill Institute for Cell and Molecular Biology, Cornell University, Ithaca, NY, USA.
  • Gupta S; Center for Advanced Proteomics, Cornell University, Ithaca, NY, USA.
  • Paramo MI; Weill Institute for Cell and Molecular Biology, Cornell University, Ithaca, NY, USA.
  • Hou Y; Center for Advanced Proteomics, Cornell University, Ithaca, NY, USA.
  • Mao C; Department of Computational Biology, Cornell University, Ithaca, NY, USA.
  • Luo Y; Weill Institute for Cell and Molecular Biology, Cornell University, Ithaca, NY, USA.
  • Judd J; Center for Advanced Proteomics, Cornell University, Ithaca, NY, USA.
  • Wierbowski S; Department of Molecular Biology and Genetics, Cornell University, Ithaca, NY, USA.
  • Bertolotti M; Genomic Medicine Institute, Lerner Research Institute, Cleveland Clinic, Cleveland, OH, USA.
  • Nerkar M; Division of Health and Biomedical Informatics, Department of Preventive Medicine, Northwestern University, Chicago, IL, USA.
  • Jehi L; Division of Health and Biomedical Informatics, Department of Preventive Medicine, Northwestern University, Chicago, IL, USA.
  • Drayman N; Department of Molecular Biology and Genetics, Cornell University, Ithaca, NY, USA.
  • Nicolaescu V; Weill Institute for Cell and Molecular Biology, Cornell University, Ithaca, NY, USA.
  • Gula H; Center for Advanced Proteomics, Cornell University, Ithaca, NY, USA.
  • Tay S; Department of Computational Biology, Cornell University, Ithaca, NY, USA.
  • Randall G; Weill Institute for Cell and Molecular Biology, Cornell University, Ithaca, NY, USA.
  • Wang P; Center for Advanced Proteomics, Cornell University, Ithaca, NY, USA.
  • Lis JT; Department of Molecular Biology and Genetics, Cornell University, Ithaca, NY, USA.
  • Feschotte C; Lerner Research Institute, Cleveland Clinic, Cleveland, OH, USA.
  • Erzurum SC; Department of Molecular Biology and Biochemistry, University of California, Irvine, Irvine, CA, USA.
  • Cheng F; Department of Microbiology, Ricketts Laboratory, University of Chicago, Chicago, IL, USA.
  • Yu H; Department of Microbiology, Ricketts Laboratory, University of Chicago, Chicago, IL, USA.
Nat Biotechnol ; 41(1): 128-139, 2023 01.
Article in En | MEDLINE | ID: mdl-36217030
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Full text: 1 Collection: 01-internacional Database: MEDLINE Main subject: Protein Interaction Mapping / COVID-19 Type of study: Prognostic_studies Limits: Humans Language: En Journal: Nat Biotechnol Journal subject: BIOTECNOLOGIA Year: 2023 Document type: Article Affiliation country: United States Country of publication: United States
Fulltext
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Full text: 1 Collection: 01-internacional Database: MEDLINE Main subject: Protein Interaction Mapping / COVID-19 Type of study: Prognostic_studies Limits: Humans Language: En Journal: Nat Biotechnol Journal subject: BIOTECNOLOGIA Year: 2023 Document type: Article Affiliation country: United States Country of publication: United States