Lung adenocarcinoma harboring complex EML4-ALK fusion and BRAF V600E co-mutation responded to alectinib.

Guo, Weihong; Liang, Jianping; Zhang, Dandan; Huang, Xikun; Lv, Yanhua

Guo, Weihong; Liang, Jianping; Zhang, Dandan; Huang, Xikun; Lv, Yanhua.

Affiliation

Guo W; Zhongshan City People's Hostipial, Zhongshan, Guangdong Province, China.

Medicine (Baltimore) ; 101(40): e30913, 2022 Oct 07.

Article in En | MEDLINE | ID: mdl-36221356

Subject(s)

Adenocarcinoma of Lung; Carcinoma, Non-Small-Cell Lung; Lung Neoplasms; Adenocarcinoma of Lung/drug therapy; Adenocarcinoma of Lung/genetics; Anaplastic Lymphoma Kinase/genetics; Carbazoles; Carcinoma, Non-Small-Cell Lung/drug therapy; Carcinoma, Non-Small-Cell Lung/genetics; Carcinoma, Non-Small-Cell Lung/pathology; Humans; Lung Neoplasms/drug therapy; Lung Neoplasms/genetics; Lung Neoplasms/pathology; Male; Microtubule-Associated Proteins/genetics; Middle Aged; Mutation; Oncogene Proteins, Fusion/genetics; Piperidines; Protein Kinase Inhibitors/pharmacology; Protein Kinase Inhibitors/therapeutic use; Proto-Oncogene Proteins B-raf/genetics; RNA

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Full text: 1 Collection: 01-internacional Database: MEDLINE Main subject: Carcinoma, Non-Small-Cell Lung / Adenocarcinoma of Lung / Lung Neoplasms Type of study: Prognostic_studies Limits: Humans / Male / Middle aged Language: En Journal: Medicine (Baltimore) Year: 2022 Document type: Article Affiliation country: China Country of publication: United States

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