Insight Into Factors Governing Formation, Synthesis and Stereochemical Configuration of DNA Adducts Formed by Mitomycins.

Paz, Manuel M; Champeil, Elise

Paz, Manuel M; Champeil, Elise.

Affiliation

Paz MM; Instituto de Materiais (iMATUS), Departamento de Química Orgánica, Facultad de Química, Universidade de Santiago de Compostela, Santiago de Compostela, A Coruña, 15782, Spain.
Champeil E; Department of sciences, John Jay College of Criminal Justice, 524 West 59th street, New York, NY, 10019, United States.

Chem Rec ; 23(1): e202200193, 2023 Jan.

Article in En | MEDLINE | ID: mdl-36251922

Subject(s)

DNA Adducts; Mitomycin; Mitomycin/pharmacology; Mitomycin/chemistry; Mitomycin/metabolism; DNA/chemistry; Oligonucleotides

Key words

DNA adducts; Mitomycin C; Reductive activation; Site-specific alkylation; Structure-activity relationship

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Full text: 1 Collection: 01-internacional Database: MEDLINE Main subject: Mitomycin / DNA Adducts Language: En Journal: Chem Rec Journal subject: QUIMICA Year: 2023 Document type: Article Affiliation country: Spain Country of publication: United States

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